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KEGG   Bufo bufo (common toad): 120981059
Entry
120981059         CDS       T07950                                 
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
bbuf  Bufo bufo (common toad)
Pathway
bbuf00562  Inositol phosphate metabolism
bbuf01100  Metabolic pathways
bbuf04012  ErbB signaling pathway
bbuf04020  Calcium signaling pathway
bbuf04070  Phosphatidylinositol signaling system
bbuf04370  VEGF signaling pathway
bbuf04625  C-type lectin receptor signaling pathway
Module
bbuf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:bbuf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120981059 (PLCG2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    120981059 (PLCG2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbuf04131]
    120981059 (PLCG2)
Enzymes [BR:bbuf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     120981059 (PLCG2)
Membrane trafficking [BR:bbuf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    120981059 (PLCG2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    120981059 (PLCG2)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y SH2 EF-hand_PLCG2 C2 SH3_1 SH3_9 PH PH_12 EF-hand_PLCG1 SH2_1 PH_14 SH3_2 EF-hand_like
Other DBs
NCBI-GeneID: 120981059
NCBI-ProteinID: XP_040266464
Position
10:complement(141303694..141430639)
AA seq 1257 aa
MARQKSSDYWVLPEYEKSQIKRTLELGTVMTVFNYKKSQPERRTIQVIMETFQVAWSKTA
DKLEGFLDLCEIKEIRLGKNCKDFERGKASRLKEDCCFTIFYGSQFVLNTLSLEADSVDD
AERWQRGLNILLEEVNQASTPTIIESWLRKQIYSMDQTRRNSISVRELKTILPQINYKVG
SAKFLKDKLVDIGIPRDDLSFEHVHMFYKRLMFDHQRSILDEFRKDTSVFILGNVDRADA
SAVYLHDFQRFLQHEQQESSAQDINKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSKE
NSIWDEKYDEITVQNMNNPLSHYWIASSHNTYLTGDQLRSESSTEAYVRCLRMGCRCVEL
DCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSEYPVILSIEEHCTVEQQRYMA
KVFKEVFGDMLLTKPTEASADQLPSPTQLKEKIIIKHKKLGPKGDYVTNADDHKEETKLQ
GELYMWDAIDQKWSVRYCAIAGDKLSYGDEIEQNSEDPTPKSMKDQHLQEKWFQLTEGRN
MAERLLQEYCAEMGGKDGTFLVRASGTFPDECTLSFWRSGRVQHCRIYSCSDGEYVKYYL
TDNLTFNSIYELIQHYKKFSLRCPDFELRLTDGVPNPNPHLSEDWYYDNLSRGEAEEMLM
RIPRDGAFLIRRRENLTSYAITFRAEGKIKHCRITKDGRLFVLGTSAYFENLVELVNYYE
KHALYRKIKLRYPVTEELLSRLNAEKDLSSIYGVNTVYVDPNEISPAMPQGTVRALYNYT
ATRPDELSFCTGALIHNVAKVSDGWWTGDYGDKLQHFFPSNYVEDISMNDDSVINRIIED
SPLGAMCRGILDLGTYEIKKLVQGKHNKLFVFSLEPKDQKDPSVDFAAEKVEELFEWYKN
IHTIIHRKGAEDYFIKTCEKNQAIAKEMSDMVIYCKPRSEAKDNLERPDFREIRSFVENK
AESISRQKPLELLRYNRRALTRVYPKGPRVDSSNYDPLHLWLCGSQMVALNYQTPDRYMQ
INDAMFSHNGRCGYILQPECMRQDSFDPSASTRRGQMVLTIKVIGARHLPKPGRGIACPF
VEIEICGGEYDNNKFRTSVVNDNGLNPVWTAIQQQALFEIHEPDLAFLRFVVYEEDMFSD
PNFLAQSTFPLKGLKTGYRSVPLKNGYGENIELASLLVYCHIQKYLGLGEELYSTSAMMG
HNNELALYDTHKAVRGIPGREPNRQHVLEGSGAAVPDPGKRLGTKQISNSKFYIGLQ
NT seq 3774 nt   +upstreamnt  +downstreamnt
atggcgcggcagaaaagctccgattactgggttctcccggagtatgagaagagccagata
aagaggactcttgaactgggcacggtaatgactgtatttaactacaagaagtctcagcct
gagcgaaggaccatccaggtcataatggaaaccttccaggtggcctggagcaagactgct
gataaacttgaaggattcttggacctttgtgaaattaaggaaatccgtctgggaaaaaac
tgcaaggatttcgagcgtggaaaagcctcccgactgaaggaagattgctgcttcactatc
ttctatggaagccagtttgtccttaacacgttaagtctggaagcggactctgtggatgat
gctgagaggtggcaacgtgggttgaacattttacttgaagaagtgaaccaggcatccacc
ccaaccatcatagaaagctggctgaggaagcagatctactccatggatcagaccagaagg
aacagtattagcgttcgagagctgaagaccatactccctcagataaactacaaagtcgga
agtgcaaaattcctgaaagacaagctggtggacattgggatccctagagatgacctcagt
tttgagcatgtccatatgttctacaaaagactgatgttcgaccatcagcgatctattctg
gatgaattcaggaaagatacttcagtatttattttgggaaacgtggatcgagctgatgcc
tccgctgtttatttgcacgactttcagaggtttttacaacatgagcaacaggaatcctcg
gcccaggatattaataaggttcgtgaacgcatgacgaagtttattgacgacactatgagg
gagacggcggagccctttctgttcgtggacgagtttctgacctacttattttccaaagaa
aacagcatctgggatgagaagtatgatgagattactgtgcagaacatgaataatccgctg
tcacattactggattgcttcctcacataacacgtatttaacaggagaccagctgcgcagc
gagtcgtccacagaagcctatgtgcggtgtctgcggatggggtgccgatgtgtggagttg
gactgctgggacggccctgatggaaagccaattatttatcacggatggacaagaacaacg
aaaattaaatttgacgacgtggtgcaagctattaaggaccatgcatttgtcacctctgaa
tacccggtcattctctccattgaagagcattgcacggtggagcagcagaggtatatggcc
aaagtgtttaaagaagtgttcggtgacatgctgttgaccaaacccaccgaagcaagtgcg
gaccagctaccatctcctactcagctaaaggagaaaatcattatcaagcataaaaaattg
ggacccaaaggcgattacgtcaccaatgcagacgaccataaggaggaaacaaagctccag
ggagaactgtacatgtgggacgcaatagatcagaaatggtccgtgcgttactgcgccatc
gccggtgataaactgtcctatggtgatgagattgagcagaattcagaggaccctacacct
aagtcaatgaaagatcaacacttgcaagaaaaatggttccagttgactgaaggccgaaat
atggcggagcgccttctgcaggagtactgtgctgagatggggggcaaagacggaaccttc
ttagtgagagcgagtggaaccttcccggatgagtgcacgctctctttctggagatcgggc
agagtgcagcactgtcgaatctactcctgctcggacggagagtacgtcaagtattacctg
accgacaacctaacattcaatagcatttatgaactgatacaacactacaagaagttctct
ctgcggtgtcccgacttcgagctgaggttaacagacggcgttcccaaccccaatccacac
ttatctgaggactggtactacgataaccttagtcgaggagaagcagaggaaatgctgatg
agaattcctcgggatggtgcttttctgatacggaggagagaaaatctgacctcttacgct
attactttcagggcagagggaaaaattaagcactgcagaatcacaaaagatggccgcctg
tttgttcttgggacttcagcctattttgagaatttggtggaactggttaattattatgag
aagcatgcattgtaccgaaaaattaagctacgctacccggtgacggaggagctgctgagc
agactgaacgccgaaaaggacttgagctccatttacggagttaatacagtgtacgtggat
cccaatgaaatctccccagccatgccacaagggacggtccgagcgctatacaactatacg
gccacgagacctgacgagctgagtttctgcaccggcgccctgattcacaacgtggctaaa
gtctctgacggatggtggacgggggactacggagataagctgcagcacttcttcccctca
aactatgtagaggacatatcaatgaatgatgacagcgttatcaaccggattattgaagac
agtcccttgggggcaatgtgtagaggtatcctagaccttgggacatatgaaatcaaaaaa
ttggtgcaaggcaaacacaacaaactgtttgtcttttcactggaacccaaggaccagaag
gatccctcagtagattttgcagctgagaaagtggaagagctgttcgaatggtacaaaaat
atccatactataatacaccggaaaggggcagaggattacttcatcaagacctgtgagaag
aatcaggctattgcaaaagagatgtcggacatggtcatttactgcaaaccaaggagtgag
gccaaggacaacttagagagacctgatttccgagaaatccggtcgtttgttgagaataaa
gcagaaagcatctcaagacagaaacccctcgagcttctgagatataaccgcagagcttta
actcgggtctacccaaaaggaccgcgagtagactcctctaactatgaccctctgcacctg
tggttatgtggatcccagatggttgctctgaactaccagacaccagatcgttacatgcag
ataaatgatgccatgttctcccacaatggccgatgtggatatattttacaaccagagtgt
atgagacaagactcctttgacccgagtgcttcaacgagacggggacaaatggttttgacc
attaaggtgatcggagctcgtcacctgccgaagccaggacgtggtattgcctgtccattt
gtagagatagagatatgtggcggagaatatgacaacaacaagttccgaaccagtgttgtc
aatgacaatggcttaaaccccgtgtggaccgctattcagcagcaggccttgtttgagatc
catgaaccagacctggcgtttctgaggtttgtggtatacgaagaagacatgttcagtgac
ccgaacttcttggcgcaaagtacatttcctttaaagggtctgaaaacaggttacagatcg
gtgccactcaaaaatggctatggtgaaaatatagaactggcttccctcctggtctactgc
catatacaaaaatacctgggactaggagaagagctgtattcaacatccgctatgatgggc
cataataatgaactggcattatacgacacgcacaaggccgtaagggggatacctggcaga
gaacccaataggcaacatgtgctggaaggcagtggagctgcagtcccagatcctggtaaa
cggttaggaacgaaacagatcagtaacagcaaattttacattggtctacaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (14)   
   Pfam (14)   
All databases (45)   

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