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KEGG   Bubalus bubalis (water buffalo): 102398970
Entry
102398970         CDS       T05912                                 
Symbol
GCK
Name
(RefSeq) hexokinase-4
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub00010  Glycolysis / Gluconeogenesis
bbub00052  Galactose metabolism
bbub00500  Starch and sucrose metabolism
bbub00520  Amino sugar and nucleotide sugar metabolism
bbub00524  Neomycin, kanamycin and gentamicin biosynthesis
bbub01100  Metabolic pathways
bbub01200  Carbon metabolism
bbub01250  Biosynthesis of nucleotide sugars
bbub04910  Insulin signaling pathway
bbub04911  Insulin secretion
bbub04917  Prolactin signaling pathway
bbub04922  Glucagon signaling pathway
bbub04930  Type II diabetes mellitus
bbub04950  Maturity onset diabetes of the young
bbub05230  Central carbon metabolism in cancer
Module
bbub_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
bbub_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102398970 (GCK)
   00052 Galactose metabolism
    102398970 (GCK)
   00500 Starch and sucrose metabolism
    102398970 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    102398970 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    102398970 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102398970 (GCK)
   04922 Glucagon signaling pathway
    102398970 (GCK)
   04917 Prolactin signaling pathway
    102398970 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    102398970 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102398970 (GCK)
   04950 Maturity onset diabetes of the young
    102398970 (GCK)
Enzymes [BR:bbub01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     102398970 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 102398970
NCBI-ProteinID: XP_025147150
Position
8:76665524..76702062
AA seq 465 aa
MLDDRARMEISKKEKAEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHKEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTTHQMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQN
VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE
LVRLVLLKLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPS
ATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK
ERFHAIVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1398 nt   +upstreamnt  +downstreamnt
atgctggatgacagagccaggatggagatctccaagaaggaaaaggcggaacagatcctg
gcagagttccagctgcaggaggaggacttgaagaaggtgatgaggcggatgcagaaggag
atggaccgaggcctgaggctggagacccacaaggaggccagtgtgaagatgctgcccacc
tacgtgcgctccaccccagagggctcagaggttggggacttcctctccctggacctgggt
ggcaccaacttccgggtgatgctggtgaaggtgggagaaggcgaggcgggacagtggagt
gtgaagaccacacaccagatgtactccatccccgaggatgccatgacgggtactgctgag
atgctctttgactacatctctgagtgcatttctgacttcctggataagcatcagatgaag
cataagaagctgcccttgggcttcaccttctcctttcccgtgaggcatgaagacattgac
aagggcatccttctcaactggaccaagggcttcaaggcctcgggagcagaaggcaacaac
attgtggggctcctgcgagatgccatcaagcggagaggtgactttgagatggacgtggtg
gcaatggtgaatgacactgtggccacgatgatctcctgctactatgaagaccgccggtgt
gaggttggcatgattgtgggcacgggctgcaacgcttgctacatggaggagatgcagaac
gtggagctggtggaaggggacgagggccgcatgtgtgtcaacaccgagtggggcgccttc
ggggactcaggcgagctggacgagttcctgctggagtacgaccgcgtggtggatgagaac
tccctgaaccccggccagcagctgtacgagaaactcatcggtggcaagtacatgggtgag
ctggtgcggcttgtgctgctgaagcttgtggacgagaatctgctcttccacggagaggcc
tcggagcagctgcgcacgcgcggcgccttcgagacacgcttcgtgtctcaggtggagagc
gattccggtgaccgcaagcagatctacaatatcctgagcactctagggctgcgaccctcg
gccactgactgtgacatcgtgcgccgagcctgcgaaagcgtgtccacgcgcgccgcgcac
atgtgcgccgcgggactggcgggcgtcatcaaccggatgcgcgagagccgcagcgaggac
gtgatgcgcatcaccgtgggcgtggacggctccgtgtacaagctgcaccccagcttcaag
gagcggttccacgccatcgtgcgcaggctgacgcccagctgtgaaatcaccttcattgag
tcggaggagggcagcggccggggcgcggccttgatctccgcggtggcctgtaagaaggcc
tgcatgctgggccagtaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (8)   

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