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KEGG   Ailuropoda melanoleuca (giant panda): 100476678
Entry
100476678         CDS       T01329                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04010  MAPK signaling pathway
aml04015  Rap1 signaling pathway
aml04218  Cellular senescence
aml04620  Toll-like receptor signaling pathway
aml04664  Fc epsilon RI signaling pathway
aml04668  TNF signaling pathway
aml04714  Thermogenesis
aml04750  Inflammatory mediator regulation of TRP channels
aml04912  GnRH signaling pathway
aml04935  Growth hormone synthesis, secretion and action
aml04936  Alcoholic liver disease
aml05014  Amyotrophic lateral sclerosis
aml05022  Pathways of neurodegeneration - multiple diseases
aml05132  Salmonella infection
aml05135  Yersinia infection
aml05145  Toxoplasmosis
aml05161  Hepatitis B
aml05169  Epstein-Barr virus infection
aml05170  Human immunodeficiency virus 1 infection
aml05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
aml05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100476678 (MAP2K3)
   04668 TNF signaling pathway
    100476678 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100476678 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    100476678 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    100476678 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100476678 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    100476678 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100476678 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100476678 (MAP2K3)
   05161 Hepatitis B
    100476678 (MAP2K3)
   05169 Epstein-Barr virus infection
    100476678 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100476678 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100476678 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100476678 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    100476678 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100476678 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100476678 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100476678 (MAP2K3)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100476678 (MAP2K3)
Protein kinases [BR:aml01001]
 Serine/threonine kinases: STE group
  STE7 family
   100476678 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Haspin_kinase Seadorna_VP7 APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 100476678
NCBI-ProteinID: XP_002928983
Ensembl: ENSAMEG00000012302
UniProt: G1M0W7
Position
17:13096205..13124414
AA seq 347 aa
MESPDSSQPASMPQTKGKSKRKKDLRISCLSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSVVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERLSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgactccagtcagcccgccagcatgccccagaccaaagggaaatccaaa
aggaagaaggatttacggatatcctgcctgtccaagccgcccgtacccaaccccacaccc
cctcggaacctggactcccggaccttcatcaccatcggagacaggaactttgaggtggag
gccgatgacctggtgaccatctcagagctgggccgcggagcctatggggtggtggagaag
gtgcggcatgcccagagcggcaccatcatggccgttaagcggatccgggccaccgtgaac
tcgcaggagcagaagcgtctgctcatggacttggacatcaacatgcgaacggtcgactgc
ttttacaccgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgctcgataaaaacatgact
attccagaggacatcctgggggaaattgctgtgtctgtcgtgagggcgttggaacacctg
cacagcaagctgtccgtgatccacagagacgtgaagccatccaatgtcctcatcaacaag
gagggtcatgtgaagatgtgtgactttggtatcagtggctacttggtggattctgtggcc
aagacgctggatgctggctgcaagccctacatggctcccgagagaatcaacccagagctg
aaccagaaaggctacaacgtcaagtccgacgtctggagcctgggcatcaccatgatcgag
atggccatcctccgctttccgtacgaatcctgggggaccccgttccagcagctgaagcag
gtcgtcgaagagccgtctccccagcttcctgccgaccgtttctctcctgagtttgtggac
ttcactgcacagtgcttgagaaagaaccccgcggagcgtctgagctacttggagctgatg
gagcacccgttcttcacattgcacaaaaccaagaagacggacattgctgcctttgtgaag
gagatcctgggggaggactcgtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (48)   

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