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KEGG   Acinonyx jubatus (cheetah): 106986998
Entry
106986998         CDS       T04657                                 
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
aju  Acinonyx jubatus (cheetah)
Pathway
aju04010  MAPK signaling pathway
aju04020  Calcium signaling pathway
aju04022  cGMP-PKG signaling pathway
aju04024  cAMP signaling pathway
aju04218  Cellular senescence
aju04260  Cardiac muscle contraction
aju04261  Adrenergic signaling in cardiomyocytes
aju04270  Vascular smooth muscle contraction
aju04530  Tight junction
aju04713  Circadian entrainment
aju04723  Retrograde endocannabinoid signaling
aju04724  Glutamatergic synapse
aju04725  Cholinergic synapse
aju04726  Serotonergic synapse
aju04727  GABAergic synapse
aju04728  Dopaminergic synapse
aju04911  Insulin secretion
aju04912  GnRH signaling pathway
aju04921  Oxytocin signaling pathway
aju04924  Renin secretion
aju04925  Aldosterone synthesis and secretion
aju04927  Cortisol synthesis and secretion
aju04929  GnRH secretion
aju04930  Type II diabetes mellitus
aju04934  Cushing syndrome
aju04935  Growth hormone synthesis, secretion and action
aju04973  Carbohydrate digestion and absorption
aju05010  Alzheimer disease
aju05020  Prion disease
aju05022  Pathways of neurodegeneration - multiple diseases
aju05031  Amphetamine addiction
aju05207  Chemical carcinogenesis - receptor activation
aju05410  Hypertrophic cardiomyopathy
aju05412  Arrhythmogenic right ventricular cardiomyopathy
aju05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:aju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    106986998
   04022 cGMP-PKG signaling pathway
    106986998
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    106986998
   04929 GnRH secretion
    106986998
   04921 Oxytocin signaling pathway
    106986998
   04935 Growth hormone synthesis, secretion and action
    106986998
   04924 Renin secretion
    106986998
   04925 Aldosterone synthesis and secretion
    106986998
   04927 Cortisol synthesis and secretion
    106986998
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    106986998
  09156 Nervous system
   04724 Glutamatergic synapse
    106986998
   04727 GABAergic synapse
    106986998
   04725 Cholinergic synapse
    106986998
   04728 Dopaminergic synapse
    106986998
   04726 Serotonergic synapse
    106986998
   04723 Retrograde endocannabinoid signaling
    106986998
  09159 Environmental adaptation
   04713 Circadian entrainment
    106986998
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    106986998
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106986998
   05020 Prion disease
    106986998
   05022 Pathways of neurodegeneration - multiple diseases
    106986998
  09165 Substance dependence
   05031 Amphetamine addiction
    106986998
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    106986998
   05412 Arrhythmogenic right ventricular cardiomyopathy
    106986998
   05414 Dilated cardiomyopathy
    106986998
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    106986998
   04934 Cushing syndrome
    106986998
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:aju04040]
    106986998
Ion channels [BR:aju04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   106986998
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 106986998
NCBI-ProteinID: XP_026894768
UniProt: A0A6J1XQN2
Position
A2:complement(143838449..144143530)
AA seq 2209 aa
MMMMMMMKNMHHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDVIAEEDPAPCAFSGNGRQCAANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GGGENQGGCGSLWCWWKRRGTAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMAT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
IYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHHEQSKIFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADHYFTDAWNTF
DALIVVGSVVDIAITEVNPTESDNVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSR
GEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTF
PQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYSPGEEYTCGSNFAIVYFISFYMLCA
FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRI
QPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEE
LRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYP
AKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEEDVFKRNGALLGNHVNH
VNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQAPS
STNANLNNANMSKAAPGKRPSIGNLEHMSENGHHSSHKRDREAQRRSSIKRTRYYETYIR
SDSGDEQFPTICREDPEVHGYFSDPRCLEEQEYFSGEEGSEDAGSPAGSRQNYSYYNRYP
GSNWDFERPRGYHHPQGFLEDDDSPICYDSRRSPRRRLLPPTPTSRRRSSFNFECLRRQS
SQEEAPPPPAFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRD
WTPCYAPLIQVERPEALDQVNGSLPSLHRSSWYTDEPGISYRTFTPASLTVPSSFRNKNS
DKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASNLLNGTVH
PRANGGVGPMSHRQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITTL
NT seq 6630 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaacatgcaccatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctccgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatatgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgtgcccttttctgtttatcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcatatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcaggaggcttcgatgtcaaagccctccga
gcctttcgagtgttacgaccacttcgactagtgtcaggagtacccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatgtcatagctgaagaggacccagcgccgtgtgcgttctca
gggaatggacgccagtgtgccgccaatggcacggagtgtaggagtggctgggttggccca
aatgggggcatcaccaacttcgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagatgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattctcaaaggaaagagagaaggctaaagcccgggga
gatttccagaagctccgggagaagcagcagctagaggaggatctaaagggctacttggat
tggatcacccaagcagaggacatcgatcctgagaacgaggaagaaggaggagaggaaagc
aaacgcaacaccagcatgccgaccagcgagacagagtctgtgaacacggagaacgtaagt
ggtggaggcgagaaccaaggcggctgtgggagtctctggtgctggtggaagcgaagaggc
acggccaaggctgggccctctgggtgtcggcggtggggccaagccatctcaaaatccaag
ctcagccgccgctggcgccgctggaaccgattcaatcgcaggagatgtagggctgctgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagcctgattggttgacgcagattcaagatatcgctaacaaa
gtcctcctggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggtctccag
gcgtatttcgtctctctttttaatcggtttgactgcttcgtggtatgtggtggaattact
gaaaccatcctggtggagctggaaatcatgtctcccctggggatctctgtgtttcggtgt
gtgcgcctcttaaggattttcaaggtgaccaggcactggacttccctgagcaacttggtg
gcctccttgttaaactccatgaagtccattgcttcgctgttgcttctgctttttctcttc
atcattatcttttccttgcttgggatgcagctgtttggtggcaagtttaattttgacgaa
acgcagaccaagcggagcacctttgacaatttccctcaagccctcctgacggtattccag
attctgacaggtgaagattggaacgctgtgatgtatgatggcatcatggcctatggtggc
ccatcgtcctcgggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaac
tatatcctactgaatgtcttcttggccatcgctgtagacaatctggctgatgctgaaagt
ttgaatactgcccagaaagaggaagctgaagagaaggaaaggaagaagattgccagaaaa
gagagcctggagaataaaaagaacaacaaaccagaggtcaaccagatagccaacagtgac
aataaggttacaattgatgactatcgagaagaggatgaagacaaggacccctacccacct
tgtgatgtgccagtaggggaagaggaagaggaggaggaagaggatgaacccgaggttcca
gctggcccccgtcctcgtagaatctcagagttgaacatgaaggagaaaatcgcccccatc
cctgaagggagtgcattcttcattctgagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccatcatatcttcaccaacctcatcctcgtcttcatcatgctgagtagc
gccgcccttgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttacagttgaaatcctgttaaagatggcgact
tttggagctttcctccacaaaggggctttctgcaggaactacttcaatctactggatatg
ctggttgtcggggtatccctggtatcattcgggatccaatccagtgccatctccgttgtg
aagattctgagggtcttaagggtcctgaggccgctcagggcgatcaacagagcgaaagga
ctcaagcacgtggtccagtgcgtcttcgtggccatccggaccatcggcaacatcatgatc
gtcaccacccttctccagttcatgttcgcctgcatcggggtccagttgttcaaggggaag
ttctatcgctgcacggacgaagccaaaagtaaccccgaagagtgcagggggcttttcatc
ctctacaaggatggggacgttgataaccctgtggtccgtgagaggatctggcaaaatagt
gatttcaactttgacaacgtcctttctgctatgatggcgctgttcacggtctccacgttt
gagggctggcctgcgttgctgtataaagccatcgactccaacggagagaatgttggcccc
atctacaactaccgtgtggagatctccatcttcttcatcatctacatcatcattgtggct
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgtcgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcaccacgagcagtccaaaatatttaatgatgccatggacattctg
aacatggtcttcactggggtgttcaccgtcgagatggttttgaaagtcattgcatttaaa
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgaccactatttcactgatgcatggaacactttt
gatgccttaattgttgttggtagcgtcgttgatattgctataactgaagtgaatccaact
gaaagtgacaatgtccctgtccccaccgctacacccgggaactctgaagagagcaataga
atctccatcacctttttccgtcttttccgagtgatgcggttggtgaagcttctcagcagg
ggggaaggcatccggacactgctgtggacttttataaagtcctttcaggcactgccctat
gtcgccctcctcatagccatgctattcttcatctacgcggttattggcatgcagatgttt
gggaaggttgctatgagagataacaaccagatcaacaggaacaacaatttccagaccttt
ccccaggcagtgctgctgctcttcaggtgtgccacaggggaagcctggcaggagatcatg
ctggcctgcctcccggggaagctctgtgaccctgagtcggattacagccctggggaggag
tacacatgtggaagcaacttcgccattgtttatttcatcagtttttacatgctctgcgca
tttctgatcatcaacctgtttgtagctgtcatcatggacaactttgattatctgacccgg
gactggtctattctggggcctcaccatttggatgaattcaaaagaatatggtcagaatat
gaccctgaggcaaagggaaggatcaagcaccttgatgtggtcactctgctccgcagaatc
cagcctcccctggggtttgggaaattatgcccacacagagtagcctgtaagagactagtt
gccatgaacatgcctctcaacagtgatgggacagtcatgtttaatgcaactctgtttgct
ttggttcggacggctcttaaaatcaagacggaagggaacctggaacaagctaatgaagag
ctccgagctgtgataaagaaaatctggaagaaaaccagcatgaaactgcttgaccaagtt
gtccctccagctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgata
caggactactttaggaaattcaagaaacggaaagaacaaggcctggtgggaaaataccct
gcgaagaacaccaccattgccctacaggcaggattaaggacactgcatgacattgggcca
gaaatccggcgtgctatatcatgtgatttgcaagatgacgagccggaggaaacaaaacga
gaagaagaagaagatgtattcaaaagaaatggtgccctgcttggaaaccatgtcaatcat
gttaatagtgataggagagattcccttcagcagaccaataccacccaccgtcccctgcat
gtccaaaggccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagca
ggaaattcggtgtgtcataaccatcataaccataattccataggaaagcaagctcccagc
tcaacaaatgccaatctcaataatgccaatatgtccaaagctgcccctggaaagcggccc
agcattgggaaccttgagcatatgtctgaaaatgggcatcactcctcccacaagcgtgac
cgtgaggctcaaagaaggtccagtattaaaagaacccgctattatgaaacttacattagg
tctgactcaggagatgagcagttcccaactatttgccgggaagatccagaggtacacggc
tacttcagcgacccccgctgcttggaggagcaggagtatttcagtggtgaggagggctct
gaggatgccggctcaccggccgggagcaggcagaactacagctactacaatagataccca
ggcagcaactgggacttcgagcggcctcgaggctaccatcatccccaaggcttcttggaa
gatgacgactcacccatttgctatgactctcggagatctccaaggagacgcctactacct
cccaccccaacatcccgccggagatcctccttcaacttcgagtgtctgcgccggcagagc
agccaggaagaggccccgccgccccccgccttcccccaccgcacagccctgcccctgcac
ctgatgcagcagcagatcatggcagttgcgggcctggattccagtaaagcccagaagtac
tcgccgagccactcaacccggtcatgggccacccctccggcgactcctccgtaccgggac
tggacaccgtgctatgcacccctgatccaggtggagcggccagaggccctggaccaggtc
aacggcagcctgccgtccctgcaccgaagctcctggtacacggacgagccgggcatctcg
taccgaactttcacaccagccagcctgactgtccccagcagcttccgcaacaaaaacagt
gacaagcagaggagcgcagacagcttggtggaagcagtcctgatatccgaaggtttagga
cggtatgcaagggacccaaaatttgtatcggccacaaaacacgaaatcgccgatgcctgt
gacttaactatcgacgagatggagagtgcagccagcaacctgctaaacgggactgtacat
ccccgggccaacgggggtgtgggccccatgtcacaccggcaggactatgagctccaggac
ttcgggccaggctacagcgatgaagagcccgaccctggaagggatgaggaggacctggca
gatgaaatgatatgcatcaccaccctgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (5)   
   Pfam (5)   
All databases (58)   

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