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KEGG   Orcinus orca (killer whale): 101277103
Entry
101277103         CDS       T05247                                 
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X4
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00061  Fatty acid biosynthesis
oor00620  Pyruvate metabolism
oor00640  Propanoate metabolism
oor01100  Metabolic pathways
oor01212  Fatty acid metabolism
oor04152  AMPK signaling pathway
oor04910  Insulin signaling pathway
oor04922  Glucagon signaling pathway
oor04936  Alcoholic liver disease
Module
oor_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    101277103 (ACACA)
   00640 Propanoate metabolism
    101277103 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    101277103 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    101277103 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    101277103 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    101277103 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101277103 (ACACA)
Enzymes [BR:oor01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     101277103 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     101277103 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     101277103 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 101277103
NCBI-ProteinID: XP_004271764
Position
19:47709683..47992734
AA seq 2383 aa
MWWSTLMSILRASSFWRWISAQTIRILRALRDHFEGIMDEPSSLAKPVELNQHSRFIIGS
VSEDNSEDEISNLVKLDLLEEKEGSLSPASVCSDTLSDLGISSLQDGLALHMRSSMSGLH
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLCVDWHENDFSKRILNVPQELYEKGCVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRK
VNNEDDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPTAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQA
ERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLSAHTLLNTVDVELIYEGVKYVL
KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC
VFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYVK
RPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNV
MNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMA
QYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHM
KAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTM
LIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESI
FLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYEL
NSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLD
NSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKIPRD
EPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNYE
VDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHL
YLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN
TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTG
KAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLL
QSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDDQG
QLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRAS
ELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSA
LNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCR
AIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHS
TVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRVIEFIPTKTPYDPRWMLAGRPH
PTQKGQWLSGFFDYGSFSEIMQPWAQTVAVGRARLGGIPVGVVAVETRTVELSIPADPAN
LDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKF
GAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGT
VEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSAAERKELESKLKEREDFLLPIYRQVA
VQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQ
IQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLAEEDGARSVIEENIKYISRDYVLKQ
IRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
NT seq 7152 nt   +upstreamnt  +downstreamnt
atgtggtggtccactctgatgtcaatcttgagggctagttctttttggaggtggatatct
gctcagacaataagaattttaagagctctgagagatcattttgaaggaataatggatgaa
ccttcttccttggccaaacctgtggagctcaaccagcactcccgattcataattggttcc
gtgtctgaagataactcagaggatgagattagcaacctggtgaagctggacctactggag
gagaaggagggctctctgtcaccagcctctgtctgctcagatacgctctctgacttgggg
atctctagcctacaggatggcttggccttacacatgaggtccagcatgtctggtttgcac
ctagtaaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttcactgtagct
tctccagcagaatttgttactcgttttggtgggaataaagtgattgagaaggttctcatt
gccaacaatggcattgcagcagtgaaatgcatgcggtctatccgccggtggtcttatgag
atgtttcgaaatgaacgtgcaattcgatttgttgtcatggtcacacctgaagacctgaaa
gccaatgcagaatacattaagatggcagatcattatgtgccagtgccaggaggaccaaac
aacaacaactatgcaaatgtggaattaattcttgacattgctaaaaggatcccagtacaa
gcagtttgggctggctggggtcatgcttctgagaatcctaagctcccagaacttcttttg
aaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttgggggataag
attgcatcttccatagtggctcaaactgcaggtatcccaactcttccatggagtggcagt
ggtctttgtgtggactggcacgaaaatgatttttcaaaacgtatcttaaatgttcctcag
gaactatatgaaaaaggttgtgtgaaggatgtggatgacgggctgaaggcagcggaggaa
gttggatatccagtaatgatcaaggcctcggaaggaggaggagggaaggggatcagaaaa
gtcaacaatgaagatgacttccctaacctcttcagacaggttcaagctgaagtccctgga
tctcctatctttgtgatgagactagccaaacagtctcgtcatctggaggtgcagatctta
gcagatcagtatggcaacgctatctctttgtttggtcgtgactgctctgtacagcgcagg
catcagaagattattgaagaggcacctactgctattgctactccagcagtatttgagcat
atggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgctgggactgtg
gaatacctctacagccaggacggcagcttctactttctggaactgaaccctcggctacag
gtggagcacccttgtacagagatggtggccgatgtcaacctccctgcggcacagctccag
attgccatggggatccctttgtatagaatcaaggatatccgtatgatgtatggggtatct
ccctggggtgatgctcccattgattttgaaaattctgctcatgttccttgcccaaggggc
cacgttattgctgctcggatcactagtgaaaatccagatgagggttttaagcccagctca
ggaacagttcaggaactgaatttccgcagcaataagaacgtttggggctatttcagtgtt
gctgctgcagggggacttcatgaatttgctgattctcagttcggtcactgcttttcctgg
ggagaaaaccgagaggaagcaatttcaaacatggtggtggctttgaaggaactatctatc
cggggcgactttcgaactacagtcgaatacctgatcaaattgttggagactgaaagcttt
cagatgaatagaattgacactggctggctggacagactgatagcagaaaaagtacaggca
gagcgacctgacaccatgttgggagttgtgtgtggggctctgcacgtggcagatgtgagc
ctgcggaatagcatctccaacttccttcactccttagagaggggtcaagtcctttctgct
catacacttctgaatacagtagatgttgaacttatctatgagggagtcaagtatgtactg
aaggtgacgcgacagtccccgaactcctacgtggtgatcatgaatggctcatgtgtggaa
gtagatgtgcatcggctgagtgatggaggactgctcttgtcctatgatggcagcagttat
accacatacatgaaggaggaggtggataggtatcgcatcacgattggcaacaaaacctgt
gtgtttgagaaggaaaatgacccttcggtgatgcgctcaccttctgctgggaagttaatc
cagtacattgtggaggatggaggccatgtgttcgctggccagtgctatgctgagatcgag
gtcatgaagatggtaatgaccttaacagctgcagagtctggctgtatccattatgtcaag
cggcctggagcagctcttgacccgggctgtgtaatagccaaaatgcagctggacaacccc
agcaaggtccagcaggctgagcttcacacaggcagtctgccgcggatccagagcacagca
ctcagaggcgagaagctccatcgagtattccactatgtcctggataatttggtcaacgtg
atgaatggatactgccttccagatcctttctttagcagcagggtaaaagactgggttgaa
cggttgatgaagaccctcagagatccctccttgcctctcctagaactgcaagatatcatg
accagtgtctctggtcgtatcccccccaatgtggagaagtctatcaagaaggaaatggct
cagtatgctagcaacatcacatcagtcctctgtcagtttcccagccagcagattgccaac
atcctagatagccacgcagctacattgaaccggaaatctgaacgggaagtcttcttcatg
aacactcagagcattgtccagctggtgcagaggtaccgcagtggtatccgaggccacatg
aaggctgtggtgatggacctgctgcggcagtacctgcgagtagagacgcaattccagaac
ggtcactatgacaaatgcgtgttcgcccttcgggaggagaacaagagtgacatgaacact
gtactgaactacatcttctctcatgctcaagtcaccaagaagaatcttctggtcacaatg
cttattgatcagttgtgtggccgggaccccactctcactgacgagctgctgaatatcctc
acggagctaactcaactcagtaagaccaccaatgctaaggtggcgctccgagcacgccag
gttcttattgcctcccatttgccatcatatgagcttcgccataaccaagtagagtctatc
ttcctatcagctattgacatgtacggacatcagttttgcattgagaacctgcagaaactc
atcttgtccgaaacgtcaattttcgatgtcctgccaaacttcttctatcacagcaaccag
gtcgtgaggatggcagctctggaggtgtatgttcgaagggcttatattgcctatgaactt
aacagtgtacaacaccgccagcttaaggacaacacctgcgtggtggaattccagttcatg
ctgcccacatctcatccaaacagagggaacatccccacgctaaacagaatgtccttctcc
tccaacctcaaccactatggcatgactcatgtagctagtgtcagcgacgtgctactggac
aactcattcactccaccgtgtcagcggatgggcggaatggtctcttttcggacttttgaa
gattttgtcaggatctttgatgaagtgatgggctgcttctgtgattccccaccccaaagc
cccacgttccctgaggcaggtcacacatctctatatgatgaagacaagatccccagggat
gaaccaattcacattctgaacgtggctatcaaaactgactgtgatatcgaggatgacagg
ctagcagctatgttccgagagtttacccagcaaaataaagctaccctggttgagcatggg
atccggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtcaactatgag
gtggatcagagatttcatagagaattccctaagtttttcacattccgagcaagggataag
tttgaggaagatcgaatctaccgtcacctggagcctgccctagctttccagttagagctg
aaccggatgagaaattttgaccttactgccatcccatgtgctaatcacaagatgcacctg
taccttggagcagccaaggtggaagtgggcacagaagtgacagactacaggttctttgtc
cgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcctttgaatatctacaa
aatgaaggggagcggctgctcctagaagccatggatgagttggaggtcgcttttaataat
acaaatgtccggactgactgcaaccacatcttcctcaactttgtgcctacagtcatcatg
gacccttcaaagattgaggagtctgtgcggagcatggtaatgcgctatggaagtcggctg
tggaagttacgtgtcctccaggcagaactgaaaatcaacattcgcctgacaccaactgga
aaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttggacatcagc
ctgtacaaggaagtgactgactccaggactgcacagatcatgtttcaggcatacggagac
aaacagggaccattacatggaatgttaatcaacactccatatgtgaccaaagacctgctt
caatcaaagaggttccaggcacagtccttagggacaacatacatatatgatatcccagag
atgtttcggcagtccctgatcaaactctgggagtctatgtccactcaagcattccttcca
tcaccccctctgccttcagacatgctgacgtacactgagcttgtgttggatgatcaaggt
caactggtccacatgaacaggcttccaggaggaaatgagattggcatggtagcttggaaa
atgacccttaaaagtccagaatatccagaaggccgagatatcattgttattggcaatgat
atcacataccgaattgggtcctttggcccccaggaggatttgctgtttctcagagcttct
gagcttgccagggcagagggcatcccacgcatctatgtagcagccaacagtggagcaaga
attggactggcagaggaaattcgtcacatgtttcacgtagcctgggtagatcctgaggat
ccttacaagggatacaaatatttatatctgacccctcaagattataagagagtcagtgct
ctcaactctgtccattgtgaacacgtggaggatgaaggagaatccaggtacaagataacc
gatattattgggaaggaagagggacttggagcagagaaccttcgaggttctggaatgatt
gctggagaatcctcgttggcctatgatgagatcatcaccattagcctggttacgtgccgg
gccattgggattggggcttaccttgtccgactgggacagagaaccatccaggttgaaaat
tctcacttaattctgacaggagctggggccctcaacaaagtcctcggaagggaagtatac
acctccaataaccagctcgggggcatccagatcatgcataacaatggggtgacccacagc
actgtctgtgatgactttgaaggggtgttcactgtcctgcactggctgtcctacatgccg
aagagtgtacacagttcagttcctctcctgaattccaaggatcctatagatagagtcatc
gagtttattcccacaaagactccatatgatcctcgctggatgctggcaggccgtccccac
ccaacccagaaaggtcagtggttgagtggattttttgactatggctctttctcggagatc
atgcagccctgggcacagactgtggcagttggcagagccaggctaggaggaatacccgtg
ggagtagttgccgtggaaacccgaaccgtggaactaagtatcccagctgatcctgcaaac
ctggattctgaagccaagataatccagcaggctggccaggtttggttcccagattctgca
tttaagacctatcaggctatcaaggacttcaaccgtgaagggctgcctctgatggtcttt
gccaactggagaggcttctctggtgggatgaaagatatgtacgaccaagtgctgaagttt
ggcgcttacatcgtggatggcttacgggagtgctcgcagcctgtgatggtttacattcct
ccacaggccgagctccggggtggctcctgggtcgtgattgaccccaccatcaacccgcgg
cacatggagatgtatgctgaccgagaaagcaggggatcagttctggagccagaagggaca
gtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtggaccccgtc
tacatccacttggctgagcgattgggcacccccgagctaagcgcagctgagcggaaggag
ctggagagcaagctgaaggagcgggaggactttctccttcccatttaccgccaggtggcc
gtgcagtttgctgacttgcacgacacaccgggccggatgcaggagaagggtgttatcaac
gacatcctggattggaagacatcccgtaccttcttctactggaggctgaggcgtctcttg
ctggaggacctggtcaagaagaaaattcacaacgccaaccccgagctgaccgacggccag
atccaggccatgttaaggcgctggtttgtggaagtggaagggacagtgaaggcctatgtt
tgggacaacaacaaggatctggtggaatggctggagaagcagctggcagaggaagatggc
gctcgctcggtaatagaggagaacatcaagtatatcagcagagactacgtcctcaagcag
atccgcagcttggtacaggccaatccagaggttgccatggattccatcgtccacatgacc
cagcacatctcgcccactcagcgagcagaagtcgttcggatcctctccacaatggactcc
ccgtcaacgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (9)   
   KEGG MODULE (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (17)   
   RefSeq(pep) (17)   
DNA sequence (17)   
   RefSeq(nuc) (17)   
Protein domain (10)   
   Pfam (10)   
All databases (86)   

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