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KEGG   Otolemur garnettii (small-eared galago): 100953767
Entry
100953767         CDS       T07855                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X2
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga04010  MAPK signaling pathway
oga04020  Calcium signaling pathway
oga04022  cGMP-PKG signaling pathway
oga04024  cAMP signaling pathway
oga04218  Cellular senescence
oga04260  Cardiac muscle contraction
oga04261  Adrenergic signaling in cardiomyocytes
oga04270  Vascular smooth muscle contraction
oga04530  Tight junction
oga04713  Circadian entrainment
oga04723  Retrograde endocannabinoid signaling
oga04724  Glutamatergic synapse
oga04725  Cholinergic synapse
oga04726  Serotonergic synapse
oga04727  GABAergic synapse
oga04728  Dopaminergic synapse
oga04911  Insulin secretion
oga04912  GnRH signaling pathway
oga04921  Oxytocin signaling pathway
oga04924  Renin secretion
oga04925  Aldosterone synthesis and secretion
oga04927  Cortisol synthesis and secretion
oga04929  GnRH secretion
oga04930  Type II diabetes mellitus
oga04934  Cushing syndrome
oga04935  Growth hormone synthesis, secretion and action
oga04973  Carbohydrate digestion and absorption
oga05010  Alzheimer disease
oga05020  Prion disease
oga05022  Pathways of neurodegeneration - multiple diseases
oga05031  Amphetamine addiction
oga05207  Chemical carcinogenesis - receptor activation
oga05410  Hypertrophic cardiomyopathy
oga05412  Arrhythmogenic right ventricular cardiomyopathy
oga05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oga00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    100953767 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    100953767 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100953767 (CACNA1D)
   04929 GnRH secretion
    100953767 (CACNA1D)
   04921 Oxytocin signaling pathway
    100953767 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    100953767 (CACNA1D)
   04924 Renin secretion
    100953767 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    100953767 (CACNA1D)
   04927 Cortisol synthesis and secretion
    100953767 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    100953767 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    100953767 (CACNA1D)
   04727 GABAergic synapse
    100953767 (CACNA1D)
   04725 Cholinergic synapse
    100953767 (CACNA1D)
   04728 Dopaminergic synapse
    100953767 (CACNA1D)
   04726 Serotonergic synapse
    100953767 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    100953767 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100953767 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100953767 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100953767 (CACNA1D)
   05020 Prion disease
    100953767 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    100953767 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    100953767 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100953767 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100953767 (CACNA1D)
   05414 Dilated cardiomyopathy
    100953767 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100953767 (CACNA1D)
   04934 Cushing syndrome
    100953767 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:oga04040]
    100953767 (CACNA1D)
Ion channels [BR:oga04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   100953767 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel PFF1_TM
Other DBs
NCBI-GeneID: 100953767
NCBI-ProteinID: XP_003789438
Position
Unknown
AA seq 2160 aa
MMMMMMMKKMQHQRQQQTDHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGETQGCCASLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTI
SSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIT
ETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLF
IIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGG
PSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARK
ESLENKKNKPEVNQIANSDNKVTIDDYQEEEEDKDPYPPCDVPVGEEEEEEEEDEPEVPA
GPRPRRISELNMKEKITPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSA
ALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDML
VVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIV
TTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEDCKGLFILYKDGDVDSPVVRERIWQNSD
FNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIVAF
FMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYV
VNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKP
KGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPTTTPGNSEESNRISITFFRLF
RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNN
QINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAI
VYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIK
HLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIK
TEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKK
RKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEEDVFKR
NGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHH
NHNSIGKHVPTSTNANLNNANMSKAAHGKRPSTGNLEHVSENGHHSSHKHDREPQRRSSI
KRTRYYETYIRSDSGDEQLPTICREDPEIHGYFRDPRCLGEQEYFSSEECYEDDSSPPAS
RQTYGYYSRYLGSNSDFERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPTSHRRS
SFNFECLRRQSSQEEVPPSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSW
ATPPATPPYQDWAPCYTPLIQVERSESLDQVNGSLPSLHRSSWYTDEPDISYRTFTPASL
TVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMES
AASTLLNGNVHPRANGDVGPTSHRQDYELQDFGPGYSDDEPDPGRDEEDLADEMICITTL
NT seq 6483 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaaacggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgctaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttatcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattcgaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacgtttttgaagatt
atagcatatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagcggcaaatcaggaggctttgacgtcaaagccctccgt
gcctttcgagtgttacgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagctccatgtgcgttctca
gggaatggacgccagtgtactgccaatggcacggaatgtcggagcggatgggtcggccct
aatggaggcatcaccaactttgataactttgcctttgccatgctcactgtgtttcagtgt
atcaccatggagggctggacagatgtgctatactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattttcaaaggaaagagagaaggctaaagcacgggga
gatttccagaagctccgggaaaagcagcagctggaagaggatctaaagggctacttggac
tggattacccaggcagaagacattgatccagagaacgaggaggaaggaggagaggaaagc
aaacgaaacactagcatgcccaccagtgagaccgaatctgtgaacacggagaacgtaagt
ggcgaaggcgagacccagggctgctgtgcaagtctctgtcaagccatttcaaaatccaaa
ctcagtcgacgctggcgtcgctggaaccgattcaatcgcagaagatgtagggctgctgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctctgagcactacaatcagccagattggttgacacagattcaagatattgctaacaaa
gtcctcttggctctgttcacctgtgagatgctggtaaaaatgtatagcttgggcctccaa
gcatattttgtctctcttttcaatcggtttgattgcttcgtggtatgtggtggaattact
gaaacaatcttagtggaactggaaatcatgtctcctctggggatctccgtgtttcgatgt
gtgcgcctcttaagaatcttcaaagtgaccaggcactggacttccctgagcaacttagtg
gcatccttgttaaactccatgaagtccatcgcttcactgttgcttctgctttttctcttc
atcatcatcttttccttgcttgggatgcagctgtttggtggcaagtttaattttgatgaa
acacaaaccaagcggagcacctttgataattttcctcaagcacttctcacggtattccag
atcctgacaggtgaggactggaatgctgtgatgtatgacggcatcatggcctacggggga
ccatcctcttcaggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaac
tatattctactgaatgtcttcttggccattgctgtagacaatttggctgatgctgaaagt
ttgaacactgctcagaaagaagaagctgaagaaaaggaaaggaaaaagattgccagaaaa
gagagcctagaaaataaaaagaacaaaccagaagtcaaccagatagccaacagtgacaac
aaggttacaattgatgactatcaagaagaggaagaagacaaggacccctacccaccttgc
gatgtgccagtaggtgaagaggaagaggaagaagaggaggatgaacctgaggttcctgct
ggtccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcacccccatccct
gaagggagtgctttcttcattctcagcaagaccaacccgatccgcgtgggctgccacaag
ctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagcagtgct
gcccttgctgctgaggaccccatccgcagccactccttccggaacactattctgggttac
tttgactatgccttcacagccatctttactgttgagatcctgttgaagatgacgactttt
ggcgcttttctccacaaaggggctttctgcagaaactacttcaatttgctggatatgctg
gttgttggggtctctctggtgtcatttgggattcaatccagtgccatctccgttgtgaag
attctgagggtcttaagggtcctgaggcccctcagggcaatcaacagagccaaaggactt
aagcacgtggtccagtgtgtctttgtggccatccgcaccattggcaacatcatgatcgtc
actacccttctccagttcatgtttgcctgcatcggggtccagttgttcaaggggaagttc
tatcgctgcacagatgaagccaaaagcaaccctgaagactgcaaggggcttttcattctc
tacaaggatggggatgttgacagccctgtagtccgtgagcggatctggcagaacagtgac
ttcaactttgacaacgtcctctctgctatgatggcactcttcaccgtgtccacgtttgag
ggctggcctgcgttgctgtataaagctatcgactcaaatggagagaacgtcggcccagtc
tacaactaccgcgtagagatctccatcttcttcatcatctacatcatcattgtagctttc
ttcatgatgaacatctttgtgggctttgtcatcgttacatttcaggagcagggggaaaaa
gagtataagaactgtgaactggacaagaatcagcgtcagtgtgttgaatacgccttgaaa
gctcgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtacgtg
gtgaactcttcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactctgc
ttggccatgcagcactacgagcagtctaagatgttcaatgatgccatggacattctgaac
atggtcttcactggggtgttcaccgttgagatggttttgaaagtcattgcatttaagcct
aaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagcatt
atagacgtggccctcagcgaagcagatccaactgaaagtgaaaatgtccctgtcccaact
actacacctgggaactctgaagaaagcaatagaatctccatcacctttttccgtcttttc
cgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacattgctgtgg
actttcattaagtcttttcaggcgctcccgtatgttgccctcctcatagccatgctgttc
ttcatctacgcggtcattggcatgcagatgtttgggaaagttgccatgagagacaacaac
cagatcaataggaacaacaatttccagacgtttcctcaggcagtactgctgctcttcagg
tgtgcgacaggtgaggcctggcaggagatcatgctggcctgcctcccgggaaagctctgc
gaccccgagtcagattacaacccaggggaggagtacacatgtgggagcaactttgctatt
gtctatttcatcagtttttacatgctctgtgcatttctgatcatcaatctttttgtggct
gttatcatggacaattttgattatctgacccgggactggtctattctggggcctcaccat
ttagatgaattcaaaagaatatggtcagaatatgaccctgaggcaaagggaaggataaaa
caccttgacgtggtcactctgcttcgacgcatccagcctcccctggggtttgggaagtta
tgtccacacagagttgcatgtaagagattagttgccatgaacatgcctcttaacagtgat
gggacagtcatgtttaatgcaaccctgtttgctttggttcgaacggctcttaagatcaag
actgaagggaacctggagcaagctaatgaagaacttcgggctgtgataaagaaaatctgg
aagaaaaccagcatgaaacttcttgaccaagttgtccctccagctggtgatgatgaggta
accgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaagaaa
cggaaagaacaaggactggtgggaaagtaccctgcgaagaacaccacaattgccctacag
gcgggattaaggacactgcatgacattgggccagaaattcggcgtgccatatcatgtgat
ttgcaagatgatgagcctgaggaaacaaaacgagaggaagaagaagatgtgttcaaaaga
aatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattccctt
cagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattccacctgca
agtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccatcat
aaccataattccataggaaagcacgttcccacctcaaccaatgccaatctcaataatgcc
aatatgtccaaagctgcccatggaaagcggcccagcactgggaaccttgagcatgtttct
gaaaatgggcatcactcctcccacaagcatgaccgggagcctcagagaaggtccagtatt
aaaagaacccgctattatgaaacttacattagatccgactcaggagatgagcagctccca
actatttgccgggaagacccagagatccatggttacttcagggacccccgctgccttggg
gagcaagaatatttcagcagtgaggagtgctatgaggacgacagctcgccacctgcgagc
aggcaaacctatggctactacagcaggtacctgggcagcaactcagacttcgagaggccc
cgaggctaccatcacccccaaggcttcctggaggacgacgactcacccgtgtgctatgat
tcacggagatctccaaggagacgcctactacctcccaccccaacatcccaccggagatcc
tccttcaacttcgagtgcctgcggcggcagagcagccaggaggaggtcccgccgtctccc
atcttcccccaccgcacagccctgcctctgcacctgatgcagcaacagatcatggcggtt
gcaggcctagattcaagtaaagcccagaagtactcgcctagtcactcaacccggtcatgg
gccacccctccagcaacccctccataccaggactgggcaccatgctacacgccgctcatc
caggtggagcggtcggagtccttggaccaggtcaatggcagcctgccgtccttgcaccgc
agctcctggtatacagacgagcccgacatctcttatcggactttcacaccagccagcctg
acagtccccagcagtttccggaacaagaacagtgacaagcagaggagcgcggacagcttg
gtggaggcagttttgatatctgaaggcttaggacgctatgcaagggacccaaaatttgtg
tcagcaacaaaacacgaaatcgccgatgcctgtgacctgaccatcgacgagatggagagt
gcagccagcacactgttaaatgggaatgtgcacccccgagccaatggggacgtgggcccc
acctcacaccgacaagactatgagctccaggactttggtcctggttacagtgacgacgag
ccagacccagggagggatgaggaggacctggcagatgagatgatatgcatcaccaccttg
tag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (6)   
   Pfam (6)   
All databases (55)   

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