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KEGG   Ornithorhynchus anatinus (platypus): 100080734
Entry
100080734         CDS       T01045                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X2
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04010  MAPK signaling pathway
oaa04015  Rap1 signaling pathway
oaa04218  Cellular senescence
oaa04620  Toll-like receptor signaling pathway
oaa04664  Fc epsilon RI signaling pathway
oaa04668  TNF signaling pathway
oaa04714  Thermogenesis
oaa04750  Inflammatory mediator regulation of TRP channels
oaa04912  GnRH signaling pathway
oaa04935  Growth hormone synthesis, secretion and action
oaa04936  Alcoholic liver disease
oaa05014  Amyotrophic lateral sclerosis
oaa05022  Pathways of neurodegeneration - multiple diseases
oaa05132  Salmonella infection
oaa05135  Yersinia infection
oaa05145  Toxoplasmosis
oaa05161  Hepatitis B
oaa05169  Epstein-Barr virus infection
oaa05170  Human immunodeficiency virus 1 infection
oaa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oaa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100080734 (MAP2K3)
   04668 TNF signaling pathway
    100080734 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100080734 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    100080734 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    100080734 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100080734 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    100080734 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100080734 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100080734 (MAP2K3)
   05161 Hepatitis B
    100080734 (MAP2K3)
   05169 Epstein-Barr virus infection
    100080734 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100080734 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100080734 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100080734 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    100080734 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100080734 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100080734 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oaa01001]
    100080734 (MAP2K3)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100080734 (MAP2K3)
Protein kinases [BR:oaa01001]
 Serine/threonine kinases: STE group
  STE7 family
   100080734 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 100080734
NCBI-ProteinID: XP_007654940
Ensembl: ENSOANG00000007732
UniProt: A0A6I8NJZ7
Position
2:35950691..36008555
AA seq 335 aa
MDKKQGKPKKRKDLKIVTIKPPVSNPTPPRNLDSRTFITIGDKNFEVEADDLVTISELGR
GAYGVVEKVRHAQSGTIMAVKRIRATVNTQEQKRLLMDLDISMRTVDCFYTVTFYGALFR
EGDVWICMELMDTSLDKFYKKVLEKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVK
PSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVW
SLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAE
RMSYLELMEHPFFNLHKTKETDIAAFVIEILGEDS
NT seq 1008 nt   +upstreamnt  +downstreamnt
atggacaagaaacaaggaaaacccaagaaaaggaaggatttaaaaatagtcaccatcaag
ccaccagtttccaaccccacgcctccccggaacctggactccaggaccttcattaccatc
ggggataagaattttgaagtggaggccgatgacttggtgaccatctcggaactgggtcgg
ggggcgtacggagtcgtggagaaagtgcggcacgcgcagagtgggaccatcatggctgtc
aagaggatccgtgcaactgtgaacactcaggaacagaagaggctgctcatggacctggac
atttcaatgaggacagtggattgcttctacactgtcacgttctatggagccctgttcaga
gagggtgatgtgtggatatgcatggagctgatggacacttccctggacaaattctataag
aaggttcttgagaagaatatgacaatcccggaagacattttgggagagatcgcagtgtcc
attgtgagagcgctggagcatttgcacagtaaattgtcggttattcacagagatgtgaaa
ccatctaatgttctcatcaacaaggaaggtcatgtgaaaatgtgtgacttcgggatcagt
ggctacttggtggactcagttgccaagaccatggatgccggttgcaagccctacatggcg
cccgagagaataaaccccgagctgaaccagaaaggttacaacgtcaagtcagatgtctgg
agtctgggaattaccatgatcgagatggccatcctccggttcccgtacgagtcctgggga
acccccttccagcaactgaagcaggtggtggaggagccctcgccccaactcccagcagac
cgtttctcccccgagtttgtggacttcacagcccagtgcttacggaagaaccctgcagag
cggatgagctacctggaacttatggaacaccccttctttaacttgcacaaaaccaaagag
actgacatcgctgccttcgtgatagagatcctgggggaggactcgtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (11)   
   Pfam (11)   
All databases (53)   

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