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KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110584435
Entry
110584435         CDS       T08474                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010  MAPK signaling pathway
nsu04015  Rap1 signaling pathway
nsu04218  Cellular senescence
nsu04620  Toll-like receptor signaling pathway
nsu04664  Fc epsilon RI signaling pathway
nsu04668  TNF signaling pathway
nsu04714  Thermogenesis
nsu04750  Inflammatory mediator regulation of TRP channels
nsu04912  GnRH signaling pathway
nsu04935  Growth hormone synthesis, secretion and action
nsu04936  Alcoholic liver disease
nsu05014  Amyotrophic lateral sclerosis
nsu05022  Pathways of neurodegeneration - multiple diseases
nsu05132  Salmonella infection
nsu05135  Yersinia infection
nsu05145  Toxoplasmosis
nsu05161  Hepatitis B
nsu05169  Epstein-Barr virus infection
nsu05170  Human immunodeficiency virus 1 infection
nsu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nsu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    110584435 (MAP2K3)
   04668 TNF signaling pathway
    110584435 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110584435 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    110584435 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    110584435 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110584435 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    110584435 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110584435 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110584435 (MAP2K3)
   05161 Hepatitis B
    110584435 (MAP2K3)
   05169 Epstein-Barr virus infection
    110584435 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    110584435 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110584435 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110584435 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    110584435 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110584435 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110584435 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nsu01001]
    110584435 (MAP2K3)
Enzymes [BR:nsu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     110584435 (MAP2K3)
Protein kinases [BR:nsu01001]
 Serine/threonine kinases: STE group
  STE7 family
   110584435 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 APH DUF4344 Choline_kinase RIO1
Other DBs
NCBI-GeneID: 110584435
NCBI-ProteinID: XP_021550151
UniProt: A0A2Y9HEE8
Position
15:12617371..12647250
AA seq 347 aa
MESPASSQPASMPQTKGKSKRKKDIRISFVSKPPVLNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHNQSDTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctccagtcagcccgccagcatgccccagaccaaagggaaatccaaa
aggaagaaggatatacggatatccttcgtgtccaagccgcccgtactcaaccctacaccc
ccccggaaccttgactcccggaccttcatcaccatcggagacaggaactttgaggtggag
gctgatgacctggtgaccatctcggagctgggccgtggggcctacggggtggtggagaag
gtgcggcataaccagagcgacaccatcatggccgttaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcgcacggtcgactgc
ttctacaccgtcaccttctatggggccctgttcagagagggagatgtgtggatctgcatg
gagctcatggacacgtccctagacaagttctaccggaaggtgctcgataaaaacatgacc
attccggaggacatcctgggggaaattgctgtgtctatcgtgagggcgctggagcatctg
cacagcaagctgtccgtgatccacagagacgtgaagccgtccaatgtcctcatcaacaag
gagggtcacgtgaagatgtgcgactttgggattagtggctacttggtggattctgtggcc
aaaacgctggacgctggctgcaaaccctacatggctcccgagaggatcaacccggagctg
aaccagaagggctacaatgtcaagtctgatgtctggagcctcggcatcaccatgatcgag
atggccatcctccgctttccgtacgaatcctgggggactccgttccagcagctgaagcag
gtggtggaagagccatctccccagctcccagctgaccgtttctctcctgagtttgtggac
ttcactgcgcagtgcttgaggaagaaccctgcggagcgcatgagctacttggagctgatg
gagcacccattcttcacgttgcacaaaacgaagaagacggacattgcggcctttgtgaag
gagatcctgggggaggactcctag

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