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KEGG   Microcebus murinus (gray mouse lemur): 105875072
Entry
105875072         CDS       T07238                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
mmur  Microcebus murinus (gray mouse lemur)
Pathway
mmur04010  MAPK signaling pathway
mmur04020  Calcium signaling pathway
mmur04022  cGMP-PKG signaling pathway
mmur04024  cAMP signaling pathway
mmur04218  Cellular senescence
mmur04260  Cardiac muscle contraction
mmur04261  Adrenergic signaling in cardiomyocytes
mmur04270  Vascular smooth muscle contraction
mmur04530  Tight junction
mmur04713  Circadian entrainment
mmur04723  Retrograde endocannabinoid signaling
mmur04724  Glutamatergic synapse
mmur04725  Cholinergic synapse
mmur04726  Serotonergic synapse
mmur04727  GABAergic synapse
mmur04728  Dopaminergic synapse
mmur04911  Insulin secretion
mmur04912  GnRH signaling pathway
mmur04921  Oxytocin signaling pathway
mmur04924  Renin secretion
mmur04925  Aldosterone synthesis and secretion
mmur04927  Cortisol synthesis and secretion
mmur04929  GnRH secretion
mmur04930  Type II diabetes mellitus
mmur04934  Cushing syndrome
mmur04935  Growth hormone synthesis, secretion and action
mmur04973  Carbohydrate digestion and absorption
mmur05010  Alzheimer disease
mmur05020  Prion disease
mmur05022  Pathways of neurodegeneration - multiple diseases
mmur05031  Amphetamine addiction
mmur05207  Chemical carcinogenesis - receptor activation
mmur05410  Hypertrophic cardiomyopathy
mmur05412  Arrhythmogenic right ventricular cardiomyopathy
mmur05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmur00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    105875072 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    105875072 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    105875072 (CACNA1D)
   04929 GnRH secretion
    105875072 (CACNA1D)
   04921 Oxytocin signaling pathway
    105875072 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    105875072 (CACNA1D)
   04924 Renin secretion
    105875072 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    105875072 (CACNA1D)
   04927 Cortisol synthesis and secretion
    105875072 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105875072 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    105875072 (CACNA1D)
   04727 GABAergic synapse
    105875072 (CACNA1D)
   04725 Cholinergic synapse
    105875072 (CACNA1D)
   04728 Dopaminergic synapse
    105875072 (CACNA1D)
   04726 Serotonergic synapse
    105875072 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    105875072 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105875072 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    105875072 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105875072 (CACNA1D)
   05020 Prion disease
    105875072 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    105875072 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    105875072 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    105875072 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    105875072 (CACNA1D)
   05414 Dilated cardiomyopathy
    105875072 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105875072 (CACNA1D)
   04934 Cushing syndrome
    105875072 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mmur04040]
    105875072 (CACNA1D)
Ion channels [BR:mmur04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   105875072 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 105875072
NCBI-ProteinID: XP_012627048
Ensembl: ENSMICG00000017510
UniProt: A0A8B7GUI5
Position
14:8480026..8794175
AA seq 2208 aa
MMMMMMMKKMQHQRQQQTDHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTTNGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGGEEGKRNTSMPTSETESVNTENVS
GEGETQGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNKPEVNQIANSDNKVAIDDYREEDEDKDPYPPC
DVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKITPIPEGSAFFILSKTNPIRVGCHK
LINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTF
GAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGL
KHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFIL
YKDGDADSPVVRERLWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPV
YNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALK
ARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILN
MVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADHYFTDAWNTFD
ALIVVGSVVDIAITEVNPTESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSRG
EGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFP
QAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYSPGEEYTCGSNFAIVYFISFYMLCAF
LIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQ
PPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEEL
RAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPA
KNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEEDVFKRNGALLGNHVNHV
NSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKHVPTS
TNANLNNANMSKAAHGKRPSLGNLEHVSENGHRSSHKHDREPQRRSNIKRTRYYETYVRS
DSGDEQLPTICREDPEICSYFRDPRCLGEQEYFSSEECYEDDSSPPGSRQACGYYSRYTG
GSSDFERPWGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSS
QEEVPLSPAFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDW
TPCYTPLIQVDRSESLDQVNGSLPSLHRSSWYTDEPDISYRTFTPASLTVPSSFRNKNSD
KQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGSARP
RANGDVGPVSHRQDYELQDFGPGYSDEEPDPGREEEDLADEMICITTL
NT seq 6627 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaaacggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcatatggattattgctgcatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagcggcaagtcaggaggctttgatgtcaaagccctccgt
gcctttcgagtgttacgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagctccgtgtgcgttctca
gggaatggacgccagtgtaccaccaatggcacggaatgtaggagcggctgggttggcccg
aacggaggcatcaccaactttgataactttgcctttgccatgctcactgtgtttcagtgc
atcactatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattttcaaaggaaagagagaaggctaaagcacgggga
gacttccagaagctccgggagaagcagcagctggaagaggatctaaagggctacttggat
tggattacgcaagcggaagatatcgatcccgagaatgaggatgaaggaggagaggaaggc
aaacgaaacacgagcatgcccaccagcgagaccgagtccgtgaacacggagaacgtgagt
ggcgaaggcgagacccagggctgctgcggaagtctctggtgctggtggagaagaagaggc
gcggccaaggctgggccctctgggtgtcggcggtggggtcaagccatctcaaaatccaaa
ctcagtcgacgctggcgtcgctggaaccggttcaatcgcagaagatgcagggctgccgtg
aagtctgtcacattttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagccagattggttgacacagattcaagatattgctaacaaa
gtcctcttggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggcctccag
gcatatttcgtctctcttttcaaccggtttgattgctttgtggtgtgcggcggaattact
gaaacgatcttggtggaactggagatcatgtctcccctgggcatctctgtgtttcggtgt
gtgcgcctcttaaggatcttcaaagtgaccaggcactggacttccctgagcaacttggtg
gcatccttgttaaactctatgaagtccattgcttcactgttgcttctgctttttctcttc
atcatcatcttttccttgcttgggatgcagctgtttggtggcaagtttaattttgatgaa
acgcaaaccaagcggagtaccttcgacaatttcccgcaagcacttctcacggtcttccag
atcctgacaggcgaagactggaatgctgtgatgtacgacggcatcatggcttacgggggc
ccgtcctcttcaggaatgattgtctgcatctacttcatcatcctcttcatttgtggtaac
tatattctactgaacgtcttcttggccattgctgtagacaatttggctgatgctgaaagt
ttgaacactgctcagaaagaagaagcagaagaaaaggaaaggaaaaagattgccagaaaa
gagagcttagaaaataaaaagaacaagccagaagtcaaccagatagccaacagtgacaac
aaggttgcaattgacgactatcgagaagaggatgaagacaaggacccctacccgccttgt
gacgtgccagtaggtgaagaggaagaagaagaggaagaggatgagcctgaggttcctgct
ggcccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcacccccatccct
gaaggcagcgctttcttcattctcagcaagaccaacccgatccgcgtgggctgccacaag
ctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagcagcgcc
gccctcgccgccgaggaccccatccgcagccactccttccggaacaccatactgggttac
tttgactatgccttcacagccatctttactgttgagatcctgttgaagatgacgactttt
ggcgctttcctccacaaaggggctttctgcaggaactacttcaatttgctggacatgctg
gttgttggggtgtctctggtgtcatttgggattcaatccagtgccatctccgtggtgaag
attctgagggtcttgagggttctgaggcccctcagggcaatcaacagagcaaaaggactt
aagcacgtggtccagtgtgtctttgtggccatccggaccatcggcaacatcatgatcgtc
accaccctcctccagttcatgtttgcctgcattggcgtccagctgttcaaggggaagttc
taccgctgcacagatgaagccaaaagtaaccccgaagagtgcagggggcttttcatcctc
tacaaggatggggatgctgacagccctgtggtccgtgagcggctctggcagaacagtgac
ttcaactttgacaacgtcctctctgccatgatggcgctcttcaccgtctccacgttcgag
ggctggcccgcgttgctgtataaagctatcgactcaaatggagagaacgtcggcccagtc
tacaaccaccgtgtggagatctccatcttcttcatcatctacatcatcattgtagctttc
ttcatgatgaacatctttgtgggctttgtcatcgttacatttcaggagcagggggaaaaa
gagtataagaactgtgagctggacaagaatcagcgtcagtgtgttgaatacgccttgaaa
gcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtacgtg
gtgaactcttcgcctttcgagtacatgatgtttgtcctcatcatgctcaacacactctgc
ttggccatgcagcactacgagcagtccaagatgttcaatgacgccatggacattctgaac
atggtcttcactggcgtgttcaccgttgagatggttttgaaagtcattgcatttaagcct
aaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagcatt
atagacgtggccctcagcgaagcagaccactatttcactgatgcatggaacacttttgat
gccttaattgttgttggtagcgtcgttgatattgctataactgaagtgaatccaactgaa
agtgaaaatgtccctgtcccaactgctacacctgggaactctgaagaaagcaatagaatc
tccatcacctttttccgtcttttccgagtgatgcgattggtgaagctactcagcaggggg
gaaggcatccggacgctgctgtggaccttcatcaagtcctttcaggcgctcccgtatgtc
gccctgctcatagccatgctgttcttcatctacgctgtcatcggcatgcagatgtttggg
aaagttgccatgagagataacaatcagatcaacaggaacaacaacttccagacatttccc
caggccgtgctgctgctcttcaggtgtgcaacgggggaggcctggcaggagatcatgctg
gcctgcctcccagggaagctctgtgaccctgagtcggactacagccctggggaggagtac
acctgtgggagcaactttgccattgtctatttcatcagcttttacatgctctgtgcattt
ctgatcatcaatctgtttgtggctgtcattatggacaattttgattatctgacccgggac
tggtctattctggggcctcaccatttagatgaattcaaaagaatatggtcagaatatgac
cctgaggcgaagggaaggataaaacacctcgacgtggtcactctgctccgccgcatccag
cctcccctggggtttgggaagttatgtccgcacagagtggcgtgcaagagattggttgcc
atgaacatgcctctcaacagtgatgggacggtaatgtttaatgcaactctctttgctttg
gttcgaacggctcttaagatcaagacagaagggaacctggaacaagctaatgaagaactc
cgggctgtgataaagaaaatctggaagaaaaccagcatgaaactgcttgaccaagttgtc
cctccagctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacag
gactactttaggaaattcaagaaacggaaagaacaaggactggtgggaaagtaccctgcg
aagaacaccacaattgccctacaggcgggattaaggacactgcacgacattgggccagaa
atccggcgtgccatatcatgtgatttgcaagatgatgagcctgaggaaacaaaacgagag
gaagaagaagatgtattcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgtt
aatagtgataggagagattcccttcagcagaccaataccacccaccgtcccctgcatgtc
caaaggccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagcagga
aattcggtgtgtcataaccatcataaccataattccataggaaagcacgttcccacctca
acaaatgccaatctcaataatgccaatatgtctaaagctgcccatggaaagcggcccagc
cttgggaaccttgagcatgtgtctgaaaatgggcatcgttcctcccacaagcatgatcgg
gagcctcagagaaggtccaatatcaaaagaacccgctattatgaaacttacgttagatcc
gactcaggagatgaacagctcccgactatttgccgggaagaccctgagatctgcagctac
ttcagggacccccgctgcctgggggagcaggaatatttcagcagcgaggagtgctatgag
gatgacagctcgccacccgggagcaggcaagcctgtggctactacagcaggtacacaggt
ggcagctcggactttgagaggccctggggctaccatcacccgcagggcttcctggaggac
gacgactcccccgtctgctacgactcacggagatctccaaggagacgcctactacctccc
accccaacatcccaccggagatcctccttcaacttcgagtgcctgcggcggcagagcagc
caggaggaggtgcccctgtcccctgccttcccccaccgcacggccttgcctctgcacctg
atgcagcaacagatcatggcagttgcaggcctagattccagtaaagcccagaagtactcg
ccgagtcactcaacccggtcatgggccacacctccagcaacccctccataccgggactgg
acaccatgctacaccccgctgatccaggtggatcggtcagagtccctggaccaggtcaac
ggcagcctgccgtccctgcaccgcagctcctggtacacagatgagcccgacatctcctat
cggactttcacaccagccagcctgaccgtccccagcagcttccggaacaagaacagcgac
aagcagaggagcgcagacagcttggtggaggcggtcttgatatctgaaggcttaggacgc
tacgcaagggacccaaaatttgtgtcggcaacaaaacacgagatcgccgatgcctgcgac
ctgaccatcgacgagatggagagtgcggccagcaccctgcttaacggcagcgcgcggccc
cgagccaacggggacgtgggccccgtctcccaccggcaggactatgagctccaggacttt
ggccctggctacagcgacgaggagccggacccgggcagagaagaggaggacctggcagac
gagatgatatgcatcaccaccttgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (28)   
   UniProt (1)   
   RefSeq(pep) (27)   
DNA sequence (27)   
   RefSeq(nuc) (27)   
Protein domain (5)   
   Pfam (5)   
All databases (102)   

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