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KEGG   Marmota marmota marmota (Alpine marmot): 107149619
Entry
107149619         CDS       T09644                                 
Symbol
Cacna1d
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma04010  MAPK signaling pathway
mmma04020  Calcium signaling pathway
mmma04022  cGMP-PKG signaling pathway
mmma04024  cAMP signaling pathway
mmma04218  Cellular senescence
mmma04260  Cardiac muscle contraction
mmma04261  Adrenergic signaling in cardiomyocytes
mmma04270  Vascular smooth muscle contraction
mmma04530  Tight junction
mmma04713  Circadian entrainment
mmma04723  Retrograde endocannabinoid signaling
mmma04724  Glutamatergic synapse
mmma04725  Cholinergic synapse
mmma04726  Serotonergic synapse
mmma04727  GABAergic synapse
mmma04728  Dopaminergic synapse
mmma04911  Insulin secretion
mmma04912  GnRH signaling pathway
mmma04921  Oxytocin signaling pathway
mmma04924  Renin secretion
mmma04925  Aldosterone synthesis and secretion
mmma04927  Cortisol synthesis and secretion
mmma04929  GnRH secretion
mmma04930  Type II diabetes mellitus
mmma04934  Cushing syndrome
mmma04935  Growth hormone synthesis, secretion and action
mmma04973  Carbohydrate digestion and absorption
mmma05010  Alzheimer disease
mmma05020  Prion disease
mmma05022  Pathways of neurodegeneration - multiple diseases
mmma05031  Amphetamine addiction
mmma05207  Chemical carcinogenesis - receptor activation
mmma05410  Hypertrophic cardiomyopathy
mmma05412  Arrhythmogenic right ventricular cardiomyopathy
mmma05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    107149619 (Cacna1d)
   04022 cGMP-PKG signaling pathway
    107149619 (Cacna1d)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    107149619 (Cacna1d)
   04929 GnRH secretion
    107149619 (Cacna1d)
   04921 Oxytocin signaling pathway
    107149619 (Cacna1d)
   04935 Growth hormone synthesis, secretion and action
    107149619 (Cacna1d)
   04924 Renin secretion
    107149619 (Cacna1d)
   04925 Aldosterone synthesis and secretion
    107149619 (Cacna1d)
   04927 Cortisol synthesis and secretion
    107149619 (Cacna1d)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    107149619 (Cacna1d)
  09156 Nervous system
   04724 Glutamatergic synapse
    107149619 (Cacna1d)
   04727 GABAergic synapse
    107149619 (Cacna1d)
   04725 Cholinergic synapse
    107149619 (Cacna1d)
   04728 Dopaminergic synapse
    107149619 (Cacna1d)
   04726 Serotonergic synapse
    107149619 (Cacna1d)
   04723 Retrograde endocannabinoid signaling
    107149619 (Cacna1d)
  09159 Environmental adaptation
   04713 Circadian entrainment
    107149619 (Cacna1d)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    107149619 (Cacna1d)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107149619 (Cacna1d)
   05020 Prion disease
    107149619 (Cacna1d)
   05022 Pathways of neurodegeneration - multiple diseases
    107149619 (Cacna1d)
  09165 Substance dependence
   05031 Amphetamine addiction
    107149619 (Cacna1d)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    107149619 (Cacna1d)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    107149619 (Cacna1d)
   05414 Dilated cardiomyopathy
    107149619 (Cacna1d)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107149619 (Cacna1d)
   04934 Cushing syndrome
    107149619 (Cacna1d)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mmma04040]
    107149619 (Cacna1d)
Ion channels [BR:mmma04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107149619 (Cacna1d)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 107149619
NCBI-ProteinID: XP_015349904
Ensembl: ENSMMMG00000010826
UniProt: A0AAJ7F305
Position
Unknown
AA seq 2181 aa
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVS
GEGETQGCCGSLWCWWKRRGTAKTGPSGCRRWGQGISNVCLSFSRRWRRWNRFNRRRCRA
AVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLG
LQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSN
LVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTV
FQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADA
ESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSENKVTIDDYREEDEDKDPY
PPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVG
CHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKM
TTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRA
KGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGL
FILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENV
GPVYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEY
ALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMD
ILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVP
VPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIA
MLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPG
KLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG
PHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPL
NSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGD
DEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAI
SCDLQDDEPEEIKREEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIP
PASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSLGNLEH
VSENGHHSSHKHDREPQRRSSIKRTRYYETYIRSDSGDEQLPTICREEADIHGYFRDPRL
GEPEYFSSEECYEDDSSPTWSRRNYSYYSRCPGSSMDFERPRGYHPPQGFWEDDDSPVGY
ESRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVPPSPALPHRAALPLHLMQQQIMA
VAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVERSESLDQVNGSLPSLH
RSSWYTDEPDISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKF
VSATKHEIADACDLTIDEMESAASTLLNGNVCPRANGDLGPASHRQDYELQDFGPGYSDE
EPDPGRDEEDLADEMICITTL
NT seq 6546 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagacttcctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcctggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctt
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
agaccagcccgcgcccttttctgtttatcactgaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
attgcatatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagcggcaaatcaggaggctttgatgtcaaagccctccgt
gccttccgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagctccatgtgcgttctca
gggaatggacgccagtgtaccgccaatggcacggaatgtaggagtggctgggttggccca
aatggaggcatcaccaattttgataactttgcctttgccatgctcactgtgtttcagtgt
atcaccatggagggctggacagatgtgctgtactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagagagaaggctaaagcgcgggga
gatttccagaaactccgggagaaacagcaactggaggaggatctcaagggctacttggat
tggatcacccaggcagaagacatcgatcctgagaatgaagaggagggtggagaggaaggc
aaacgaaataccagcatgcccaccagtgagaccgaatccgtgaacaccgagaatgtaagt
ggtgaaggcgagacccagggctgctgtggaagtctctggtgctggtggaaaagaagaggc
acagccaagacggggccctctgggtgccggcggtgggggcaaggaataagtaatgtttgc
ttatctttcagccgacgctggcgtcgctggaaccgattcaatcgtagaagatgtagagct
gccgtgaagtctgtcacgttttattggctggttattgtcctggtgtttctcaacacatta
accatttcctctgagcactacaatcagccagactggttgacgcagattcaagatatcgct
aacaaagtcctcctggctctgttcacctgtgagatgctggtaaaaatgtacagcttaggt
ctccaggcatattttgtctctctcttcaaccggtttgactgctttgtggtgtgtggcgga
attactgagaccatcttagtggaactggaaatcatgtcccctctgggaatctctgtgttc
cggtgtgtgcgcctcttgagaatcttcaaagtgaccaggcattggacctctctgagcaac
ttggtggcatccttgttaaactccatgaagtctattgcttcattgttgcttctgctcttt
ctcttcattatcatcttttccttgcttgggatgcagctgtttggaggcaagtttaatttc
gatgaaacgcaaaccaagcgaagcaccttcgacaactttccccaagcccttctgacagta
tttcagattctgacaggcgaggactggaatgctgtgatgtatgacggcatcatggcttac
ggaggcccgtcgtcctcaggaatgatcgtctgcatctacttcatcatcctcttcatctgt
ggtaactatattctactgaatgtcttcttggccatcgctgttgacaatttggctgatgcg
gaaagtttgaatactgctcagaaagaggaagctgaagaaaaggaaaggaaaaagattgcc
agaaaagagagcctagaaaataaaaagaacaacaaaccagaagtcaaccagatagccaac
agtgaaaacaaggttacaattgatgactatcgagaggaggacgaagacaaggacccttac
ccaccgtgcgatgtgccagtaggtgaagaggaagaagaggaggaagaagatgaacctgag
gttcccgctggtccccgtcctcgcagaatctcggagttgaacatgaaggagaaaattgcc
cccatccctgaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggc
tgtcacaagctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctg
agcagcgctgctcttgcggctgaggaccccatccgcagccactccttccggaacactata
ctgggttactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatg
acgacttttggagctttcctgcacaaaggggctttctgcaggaactacttcaatttgctg
gatatgctggttgttggggtatctctggtgtcatttgggattcaatccagtgccatctcc
gttgtgaagattctgagggtcttaagggtcctgaggccccttagagcgatcaacagagca
aaagggcttaagcacgtggtccagtgcgtctttgtggccatccggacaattggcaacatc
atgatcgtcaccaccctcctccagttcatgtttgcctgcattggggtgcagttattcaag
gggaagttctatcgctgcacagatgaagccaaaagtaatcctgaagaatgcaggggactt
tttatcctctacaaggatggggatgtggatagccctgtggtccgtgagaggatctggcaa
aatagcgatttcaactttgacaacgttctttctgctatgatggcgctcttcactgtctcc
acttttgagggttggcctgcgttgctgtataaagccattgactcaaatggagagaatgtt
gggccagtctacaactaccgagtggagatctccatcttcttcatcatctacatcatcatt
gtcgccttcttcatgatgaacatctttgtgggctttgtcatcgtaacatttcaggagcag
ggagaaaaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatac
gccttgaaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttc
tggtacgtggtgaactcttcgcctttcgaatacatgatgtttgtcctcatcatgctcaac
acactctgcttggccatgcagcactacgagcagtccaagatgttcaatgatgccatggac
attctgaacatggtcttcactggggtgttcactgtcgagatggttttgaaagtcattgca
tttaagcctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatc
ggcagcattatagacgtggccctcagcgaagctgacccaactgaaagtgaaaatgtccct
gtcccaactgctacacctgggaactctgaagagagcaatagaatctccatcacctttttc
cgtcttttccgagtgatgcgattggtgaagctcctcagcagaggggaaggcatccggaca
ttgctgtggacttttattaagtcctttcaggcgctcccatatgttgccctcctcatcgcc
atgctgttcttcatctacgcagtcattggcatgcagatgttcgggaaagttgccatgaga
gataataaccagatcaataggaacaacaacttccagacgtttccccaggcggtgctgctg
ctcttcaggtgtgccaccggggaggcctggcaggagatcatgttggcctgcctcccgggg
aagctctgtgaccccgagtccgattacaaccctggagaggaatacacgtgtgggagcaac
tttgccattgtctatttcatcagcttttacatgctctgtgcgtttctgatcatcaatctg
tttgtggctgtcatcatggacaattttgactatctgacacgggactggtctattctgggg
cctcaccatttagatgaattcaaacgaatatggtcagaatatgaccctgaggcaaaggga
aggataaaacaccttgacgtggtcactcttctccggcgtatccaacctcctctggggttt
gggaaattatgtccacacagagtagcgtgcaagagattagtggccatgaacatgcctctc
aacagtgatgggacagtcatgtttaacgcaaccctgtttgctttggtccgaacggctctc
aagatcaagactgaagggaacttggaacaagctaatgaagaacttcgagctgtgataaag
aaaatatggaagaaaactagcatgaaactgcttgaccaagtggtccctccagccggtgat
gatgaggtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaa
ttcaagaaacggaaagaacaaggattggtgggaaagtaccctgcgaagaacaccacaatt
gccctacaggcgggattaaggacactgcatgacattgggccagaaatccggcgtgctata
tcctgtgatttacaagatgacgagccggaggaaattaaacgagaagaagaagatgtattc
aaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagat
tcccttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattcca
cctgcaagtgacactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataac
catcataaccataattccataggaaagcaagttcccacctcaacaaatgccaatctcaat
aatgccaatatgtccaaagctgcccatggaaagcggcccagccttgggaaccttgagcat
gtatctgaaaatgggcatcattcctcccacaagcatgaccgggagcctcaaagaaggtcc
agtattaaaagaactcgctattatgaaacttacattaggtctgactcaggagatgagcag
ctcccaactatttgccgggaagaggcagacatacatggctacttcagggacccccgcttg
ggggagcccgagtatttcagcagtgaggagtgttatgaggatgacagctctcccacatgg
agcaggcgaaactacagctactacagcaggtgcccaggcagcagtatggacttcgagcgg
ccccgaggctaccaccctccccagggcttctgggaggacgatgactcccctgttggctat
gaatcacggagatctccccggagacgcctgctacctcccaccccaacatctcaccggaga
tcctccttcaactttgagtgcctgcgccggcagagcagccaggaggaggtcccgccatca
cctgcccttccacaccgagcggccctgcctctgcacctgatgcagcagcagatcatggca
gttgcaggcctggattcgagtaaagcccagaagtactcaccaagccactcaacccggtca
tgggccacccctccagcaacccctccataccgggactggacgccgtgctacacccccctg
atccaggtggaaaggtcagagtccctggaccaggtcaatggcagcctgccatccctgcac
cgcagctcctggtacacagatgagcctgacatctcctataggacattcacaccagccagc
ctgactgtccccagcagctttcggaacaaaaacagtgacaagcagaggagcgcagacagc
ttggtggaggcagtcctgatatctgaaggtttaggacgctacgcaagagatccaaaattt
gtgtcggctacaaaacatgaaatcgccgatgcttgtgacttaaccattgatgagatggaa
agtgcagccagcaccctgctcaacgggaacgtgtgtcctcgggccaacggggatctgggt
cctgcctcacaccggcaggactatgagctccaggacttcggtccaggctatagtgacgaa
gagccagaccctggacgagatgaggaagacctcgcagatgagatgatctgcatcaccacc
ttgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (5)   
   Pfam (5)   
All databases (56)   

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