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KEGG   Mesocricetus auratus (golden hamster): 101838194
Entry
101838194         CDS       T08306                                 
Symbol
Map2k3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X1
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
maua  Mesocricetus auratus (golden hamster)
Pathway
maua04010  MAPK signaling pathway
maua04015  Rap1 signaling pathway
maua04218  Cellular senescence
maua04620  Toll-like receptor signaling pathway
maua04664  Fc epsilon RI signaling pathway
maua04668  TNF signaling pathway
maua04714  Thermogenesis
maua04750  Inflammatory mediator regulation of TRP channels
maua04912  GnRH signaling pathway
maua04935  Growth hormone synthesis, secretion and action
maua04936  Alcoholic liver disease
maua05014  Amyotrophic lateral sclerosis
maua05022  Pathways of neurodegeneration - multiple diseases
maua05132  Salmonella infection
maua05135  Yersinia infection
maua05145  Toxoplasmosis
maua05161  Hepatitis B
maua05169  Epstein-Barr virus infection
maua05170  Human immunodeficiency virus 1 infection
maua05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
maua05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:maua00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101838194 (Map2k3)
   04668 TNF signaling pathway
    101838194 (Map2k3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101838194 (Map2k3)
   04664 Fc epsilon RI signaling pathway
    101838194 (Map2k3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    101838194 (Map2k3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101838194 (Map2k3)
  09159 Environmental adaptation
   04714 Thermogenesis
    101838194 (Map2k3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101838194 (Map2k3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101838194 (Map2k3)
   05161 Hepatitis B
    101838194 (Map2k3)
   05169 Epstein-Barr virus infection
    101838194 (Map2k3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101838194 (Map2k3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101838194 (Map2k3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101838194 (Map2k3)
   05022 Pathways of neurodegeneration - multiple diseases
    101838194 (Map2k3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101838194 (Map2k3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101838194 (Map2k3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:maua01001]
    101838194 (Map2k3)
Enzymes [BR:maua01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     101838194 (Map2k3)
Protein kinases [BR:maua01001]
 Serine/threonine kinases: STE group
  STE7 family
   101838194 (Map2k3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 101838194
NCBI-ProteinID: XP_040604722
Position
Unknown
AA seq 347 aa
MESPAASPPASLPQTKGKSKRKKDLRITCVSKPPAPNPTPPRNLDSRAFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADKFSPEFVD
FTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgccgcgagcccgccagccagcttgcctcagaccaaaggaaaatccaaa
aggaaaaaggatttacggataacctgtgtgtctaagccacctgcgcccaaccccacacca
ccccggaacctggactcccgggccttcatcaccatcggagacagaaacttcgaggtggag
gctgatgacttggtgaccatctcagaactgggtcgcggcgcctatggggtggtggagaag
gtgcggcatgctcagagtggcaccatcatggctgtgaagcgaatccgggccaccgtgaac
tcacaagagcagaaacgcctgcttatggacctggacatcaacatgcgcacggtcgactgc
ttctacactgtcaccttctatggtgccctcttcagagagggggatgtgtggatctgcatg
gaactcatggacacttccctggacaagttctaccggaaggtgctggagaagaacatgaca
attccggaggatatcctgggcgagattgctgtgtctatcgtgcgggccctggagcacctg
cacagcaagctgtctgtgatccacagagatgtgaagccatccaatgtcctcatcaacaag
gagggacacgtgaagatgtgcgactttggcatcagtggctacctggtggactctgtggca
aagacgatggatgctggttgcaagccttacatggctcctgagaggatcaaccctgagctg
aatcagaagggctacaatgtcaagtctgacgtctggagcctcggcatcaccatgattgag
atggccattctgcgattcccttatgagtcttgggggaccccgttccagcagctgaagcag
gtggtggaggaaccatccccacagctcccagctgacaagttctcccctgagtttgtggac
ttcactagccagtgcctaaggaagaaccctgcagagcgcatgagctacctggagctgatg
gaacaccctttcttcaccttgcacaaaactaagaagacggacattgctgcctttgtgaag
gagatcctgggagaggattcatag

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