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KEGG   REACTION: R00942
Entry
R00942                      Reaction                               
Name
tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)
Definition
ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate
Equation
Reaction class
RC00002  C00002_C00008
RC00064  C00025_C09332
RC00090  C00101_C09332
Enzyme
Pathway
rn00790  Folate biosynthesis
rn01240  Biosynthesis of cofactors
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.17
     R00942  ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate
IUBMB reaction hierarchy [BR:br08202]
 6. Ligase reactions
  6.3.2.17
   R04241  THF-polyglutamate <=> THF-polyglutamate
    R00942  Tetrahydrofolate <=> THF-L-glutamate
Orthology
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K22099  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]

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