KEGG DRUG: Finasteride and tadalafil

DRUG: Finasteride and tadalafil

Entry

D12486            Mixture   Drug

Name

Finasteride and tadalafil;
Entadfi (TN)

Product

ENTADFI (Veru)

Component

Finasteride [DR:D00321], Tadalafil [DR:D02008]

Class

Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate

Remark

ATC code:

G04CB51

Product:

D12486<US>

Efficacy

Prostatic hyperplasia treatment

Comment

Both finasteride and tadalafil are metabolized by CYP3A4.

Metabolism

Enzyme: CYP3A4 [HSA:1576]

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
    G04CB Testosterone-5-alpha reductase inhibitors
     G04CB51 Finasteride and tadalafil
      D12486  Finasteride and tadalafil <US>
USP drug classification [BR:br08302]
Genitourinary Agents
  Benign Prostatic Hypertrophy Agents
   Finasteride/ Tadalafil
    D12486  Finasteride and tadalafil
Drug groups [BR:br08330]
Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D12486  Finasteride and tadalafil
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
  D12486

Other DBs

PubChem:

497620899

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Ontology (4)   
   KEGG BRITE (4)   
Drug (1)   
   KEGG DGROUP (1)   
Chemical substance (1)   
   PubChem (1)   
All databases (6)   

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