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KEGG   DRUG: Axicabtagene ciloleucel
Entry
D11144                      Drug                                   
Name
Axicabtagene ciloleucel (USAN);
Yescarta (TN)
Product
YESCARTA (Kite Pharma)
Remark
ATC code: L01XL03
Product: D11144<US>
Efficacy
Antineoplastic, Anti-CD19 CAR-T cell
  Disease
Large B-cell lymphoma
  Type
Cellular therapy product, CAR-T cell therapy
Target
CD19 [HSA:930] [KO:K06465]
  Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04640  Hematopoietic cell lineage
hsa04662  B cell receptor signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XL Antineoplastic cell and gene therapy
     L01XL03 Axicabtagene ciloleucel
      D11144  Axicabtagene ciloleucel (USAN) <US>
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    CD19
     D11144  Axicabtagene ciloleucel (USAN) <US>
New drug approvals in the USA [br08319.html]
 Cellular and gene therapy products
  D11144
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11144
 Cellular and gene therapy products
  D11144
New drug approvals in Japan [br08318.html]
 Cellular and gene therapy products
  D11144
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11144
Other DBs
PubChem: 376219068

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Ontology (6)   
   KEGG BRITE (6)   
Chemical substance (1)   
   PubChem (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (9)   

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