| Entry |
|
|---|
| Name |
Tertatolol hydrochloride;
Artex (TN) |
|---|
| Formula |
C16H25NO2S. HCl
|
|---|
| Exact mass |
331.1373
|
|---|
| Mol weight |
331.90
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiarrhythmic, Antihypertensive, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AA Beta blocking agents, non-selective
C07AA16 Tertatolol
D08572 Tertatolol hydrochloride
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00309 Tertatolol
D08572 Tertatolol hydrochloride
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00309 Tertatolol
D08572 Tertatolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D08572 Tertatolol hydrochloride
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00309 Tertatolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00309 Tertatolol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C8x C 15.9600 -17.0800
2 C8x C 15.9600 -18.4800
3 C8x C 14.7700 -19.1800
4 C8y C 13.5800 -18.4800
5 C8y C 13.5800 -17.0800
6 C8y C 14.7700 -16.3800
7 C1x C 12.3900 -19.2500
8 C1x C 11.1300 -18.5500
9 C1x C 11.1300 -17.1500
10 S2x S 12.3200 -16.3800
11 O2a O 14.7700 -14.9800
12 C1b C 15.9600 -14.2800
13 C1c C 17.1500 -14.9800
14 C1b C 18.4800 -14.2800
15 N1b N 19.6700 -14.9800
16 C1d C 20.8600 -14.2800
17 O1a O 17.1500 -16.3800
18 C1a C 22.0781 -14.9701
19 C1a C 20.8486 -12.8800
20 C1a C 22.0724 -13.5800
21 X Cl 26.1100 -16.9400
BOND 21
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 6 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 13 17 1
19 16 18 1
20 16 19 1
21 16 20 1
|
|---|