| Entry |
|
|---|
| Name |
Ethylmorphine (BAN) |
|---|
| Formula |
C19H23NO3
|
|---|
| Exact mass |
313.1678
|
|---|
| Mol weight |
313.39
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Analgesic (narcotic), Antitussive, Opioid receptor agonist |
|---|
| Comment |
Opium alkaloid
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R05 COUGH AND COLD PREPARATIONS
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
R05DA Opium alkaloids and derivatives
R05DA01 Ethylmorphine
D07929 Ethylmorphine (BAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA06 Ethylmorphine
D07929 Ethylmorphine (BAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG01074 Ethylmorphine
D07929 Ethylmorphine
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01074 Ethylmorphine
D07929 Ethylmorphine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D07929 Ethylmorphine (BAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D07929
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Control Act Article 2 Table 1 (76 substances)
D07929
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG01074 Ethylmorphine
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01074 Ethylmorphine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 C1z C 24.0800 -18.6200
2 C8y C 24.0800 -17.2900
3 C1y C 25.2000 -19.3200
4 C1y C 22.9600 -19.2500
5 C1x C 25.2000 -17.9900
6 C8y C 22.9600 -16.6600
7 C8y C 25.2000 -16.6600
8 C1y C 26.3200 -18.6200
9 C2x C 25.2000 -20.5800
10 O2x O 21.6300 -17.9200
11 C1y C 22.9600 -20.5800
12 C1x C 27.4400 -17.9900
13 C8y C 22.9600 -15.3300
14 C1x C 26.3200 -17.3600
15 C8x C 25.2000 -15.3300
16 N1y N 27.4400 -19.3200
17 C2x C 24.0800 -21.2800
18 O1a O 21.8400 -21.2800
19 C8x C 24.1500 -14.7000
20 O2a O 21.8400 -14.7000
21 C1b C 20.6500 -15.3300
22 C1a C 28.8400 -19.3200
23 C1a C 19.4600 -14.6300
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1 #Up
5 2 6 2
6 2 7 1
7 3 8 1
8 3 9 1
9 4 10 1 #Down
10 4 11 1
11 5 12 1
12 6 13 1
13 7 14 1
14 7 15 2
15 8 16 1 #Up
16 9 17 2
17 11 18 1 #Down
18 13 19 2
19 13 20 1
20 20 21 1
21 6 10 1
22 8 14 1
23 11 17 1
24 12 16 1
25 15 19 1
26 16 22 1
27 21 23 1
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