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KEGG   DRUG: Talinolol
Entry
D07184                      Drug                                   
Name
Talinolol (INN)
Formula
C20H33N3O3
Exact mass
363.2522
Mol weight
363.49
Structure
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist (Beta blocker)
   DG01461  beta1-Adrenergic receptor antagonist
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
Remark
ATC code: C07AB13
Efficacy
Antiarrhythmic, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB13 Talinolol
      D07184  Talinolol (INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01466  Adrenergic receptor antagonist
   DG01464  beta-Adrenergic receptor antagonist (Beta blocker)
    DG01461  beta1-Adrenergic receptor antagonist
     D07184  Talinolol
  DG01653  Antiarrhythmics
   DG01806  Class II antiarrhythmic agent
    D07184  Talinolol
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D07184  Talinolol (INN)
Other DBs
CAS: 57460-41-0
PubChem: 51091522
LigandBox: D07184
NIKKAJI: J375.035C
KCF data

ATOM        26
            1   O2a O    20.5100  -24.0800
            2   C1b C    21.7000  -23.3800
            3   C1c C    22.9600  -24.0800
            4   C1b C    24.1500  -23.3800
            5   N1b N    25.3400  -24.0800
            6   C1d C    26.6000  -23.3800
            7   O1a O    22.9600  -25.4800
            8   C1a C    27.8007  -24.0999
            9   C1a C    26.6231  -21.9802
            10  C1a C    27.8124  -22.6800
            11  C8y C    20.5272  -25.4799
            12  C8x C    19.3108  -26.2024
            13  C8x C    19.3281  -27.6023
            14  C8y C    20.5491  -28.2873
            15  C8x C    21.7656  -27.5647
            16  C8x C    21.7482  -26.1648
            17  N1b N    20.5665  -29.6799
            18  C5a C    19.3729  -30.3891
            19  N1b N    18.1610  -29.7094
            20  C1y C    16.9481  -30.4304
            21  O5a O    19.3903  -31.7800
            22  C1x C    15.7292  -29.7471
            23  C1x C    14.5258  -30.4625
            24  C1x C    14.5435  -31.8623
            25  C1x C    15.7624  -32.5456
            26  C1x C    16.9658  -31.8302
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     3   7 1
            7     6   8 1
            8     6   9 1
            9     6  10 1
            10    1  11 1
            11   11  12 2
            12   12  13 1
            13   13  14 2
            14   14  15 1
            15   15  16 2
            16   11  16 1
            17   14  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   18  21 2
            22   20  22 1
            23   22  23 1
            24   23  24 1
            25   24  25 1
            26   25  26 1
            27   20  26 1

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Ontology (3)   
   KEGG BRITE (3)   
Drug (3)   
   KEGG DGROUP (2)   
   LigandBox (1)   
Chemical substance (3)   
   PubChem (1)   
   HMDB (1)   
   NIKKAJI (1)   
Gene (6)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (3)   
All databases (15)   

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