KEGG DRUG: Betamethasone and d-chlorpheniramine maleate

DRUG: Betamethasone and d-chlorpheniramine maleate

Entry

D04447            Mixture   Drug

Name

Betamethasone and d-chlorpheniramine maleate;
Celestamine (TN)

Component

Betamethasone [DR:D00244], d-Chlorpheniramine maleate [DR:D00668]

Class

Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate

Remark

Therapeutic category:

2459

ATC code:

R06AB54

Product:

D04447<JP>

Efficacy

Anti-inflammatory

Comment

Betamethasone is primarily metabolized by CYP3A4.

Metabolism

Enzyme: CYP3A4 [HSA:1576]

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AB Substituted alkylamines
     R06AB54 Chlorphenamine, combinations
      D04447  Betamethasone and d-chlorpheniramine maleate <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2  Agents affecting individual organs
  24  Hormones
   245  Adrenal hormone preparations
    2459  Others
     D04447  Betamethasone and d-chlorpheniramine maleate
Drug groups [BR:br08330]
Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D04447  Betamethasone and d-chlorpheniramine maleate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
  D04447

Other DBs

PubChem:

17398108

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Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (1)   
   KEGG DGROUP (1)   
Chemical substance (1)   
   PubChem (1)   
All databases (7)   

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