| Entry |
|
|---|
| Name |
Flestolol sulfate (USAN) |
|---|
| Formula |
C15H22FN3O4. H2SO4
|
|---|
| Exact mass |
425.1268
|
|---|
| Mol weight |
425.43
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Efficacy |
Antiarrhythmic, beta-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
D04190 Flestolol sulfate
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
D04190 Flestolol sulfate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D04190 Flestolol sulfate (USAN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 C8x C 3.6400 -5.2500
2 C8x C 3.6400 -6.6500
3 C8x C 4.8524 -7.3500
4 C8x C 6.0649 -6.6500
5 C8y C 6.0649 -5.2500
6 C8y C 4.8524 -4.5500
7 C7a C 7.2960 -4.5390
8 X F 4.8524 -3.1502
9 O7a O 8.5012 -5.2347
10 O6a O 7.2957 -3.1501
11 C1b C 9.6835 -4.5519
12 C1c C 10.8775 -5.2412
13 C1b C 12.0654 -4.5552
14 O1a O 10.8777 -6.6497
15 N1b N 13.2565 -5.2429
16 C1d C 14.4459 -4.5561
17 C1b C 15.6362 -5.2434
18 C1a C 15.4359 -3.5661
19 C1a C 13.4560 -3.5661
20 N1b N 16.8261 -4.5563
21 C5a C 18.0162 -5.2435
22 N1a N 19.2061 -4.5564
23 O5a O 18.0163 -6.6498
24 S4a S 24.6079 -5.0160
25 O1d O 26.0076 -5.0160
26 O1d O 23.2080 -5.0558
27 O1d O 24.6707 -6.4157
28 O1d O 24.6114 -3.6161
BOND 27
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 6 8 1
9 7 9 1
10 7 10 2
11 9 11 1
12 11 12 1
13 12 13 1
14 12 14 1
15 13 15 1
16 15 16 1
17 16 17 1
18 16 18 1
19 16 19 1
20 17 20 1
21 20 21 1
22 21 22 1
23 21 23 2
24 24 25 1
25 24 26 1
26 24 27 2
27 24 28 2
|
|---|