| Entry |
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|---|
| Name |
Dexpropranolol hydrochloride (USAN) |
|---|
| Formula |
C16H21NO2. HCl
|
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| Exact mass |
295.1339
|
|---|
| Mol weight |
295.80
|
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Efficacy |
Antiarrhythmic, Cardiac depressant, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Class II antiarrhythmic agent
See Propranolol [DR: D08443]
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
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| Interaction |
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| Structure map |
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| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
D03729 Dexpropranolol hydrochloride
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
D03729 Dexpropranolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D03729 Dexpropranolol hydrochloride (USAN)
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| Other DBs |
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| KCF data |
ATOM 20
1 C8x C 19.9417 -19.4715
2 C8x C 19.9417 -20.8791
3 C8x C 21.1607 -21.5830
4 C8y C 22.3798 -20.8791
5 C8y C 22.3798 -19.4715
6 C8x C 21.1607 -18.7676
7 C8x C 23.5988 -21.5830
8 C8x C 24.8179 -20.8791
9 C8x C 24.8179 -19.4715
10 C8y C 23.5988 -18.7676
11 O2a O 23.5988 -17.3600
12 C1b C 24.8200 -16.6550
13 C1c C 26.0231 -17.3498
14 C1b C 27.2163 -16.6608
15 N1b N 28.4143 -17.3528
16 C1c C 29.6102 -16.6623
17 C1a C 30.8069 -17.3535
18 C1a C 29.6104 -15.2487
19 O1a O 26.0228 -18.7210
20 X Cl 30.8000 -20.8600
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 10 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 16 18 1
20 13 19 1 #Up
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