KEGG DRUG: Crofelemer

DRUG: Crofelemer

Entry

D03605                      Drug

Name

Crofelemer (USAN);
Fulyzaq (TN);
Mytesi (TN)

Product

MYTESI (Napo Pharmaceuticals)

Remark

ATC code:

A07XA06

Product:

D03605<US>

Efficacy

Antidiarrheal

Comment

For the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy

Target

CFTR (ABCC7) [HSA:1080] [KO:K05031]
CLCA [HSA:1179 9635 22802] [KO:K05027 K05028 K05030]

Pathway

hsa04924

Renin secretion

hsa04971

Gastric acid secretion

hsa04972

Pancreatic secretion

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07X OTHER ANTIDIARRHEALS
    A07XA Other antidiarrheals
     A07XA06 Crofelemer
      D03605  Crofelemer (USAN) <US>
USP drug classification [BR:br08302]
Gastrointestinal Agents
  Anti-diarrheal Agents
   Crofelemer
    D03605  Crofelemer (USAN)
Target-based classification of drugs [BR:br08310]
Ion channels
  Other ion channels
   Chloride channel
    CLCA
     D03605  Crofelemer (USAN) <US>
Transporters
  ABC transporters
   ABCC subfamily
    CFTR (ABCC7)
     D03605  Crofelemer (USAN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
  D03605
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
  D03605

Other DBs

CAS:	148465-45-6

PubChem:

17397714

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Ontology (5)   
   KEGG BRITE (5)   
Chemical substance (1)   
   PubChem (1)   
Gene (8)   
   KEGG ORTHOLOGY (4)   
   KEGG GENES (4)   
All databases (14)   

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