| Entry |
|
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| Name |
Suxamethonium chloride hydrate (JP18);
Suxamethonium chloride dihydrate;
Succin (TN) |
|---|
| Formula |
C14H30N2O4. 2H2O. 2Cl
|
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| Exact mass |
396.1794
|
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| Mol weight |
397.33
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG01742 Quaternary ammonium compound type muscle relaxant
|
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| Remark |
| Therapeutic category: | 1224 |
| Product (DG00768): | D00766<US> D02275<JP> |
|
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| Efficacy |
Muscle relaxant |
|---|
| Comment |
Choline derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07221 | Nicotinic cholinergic receptor antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AB Choline derivatives
M03AB01 Suxamethonium
D02275 Suxamethonium chloride hydrate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
122 Skeletal muscle relaxants
1224 Cholines
D02275 Suxamethonium chloride hydrate (JP18)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG00768 Suxamethonium
D02275 Suxamethonium chloride hydrate
DG01742 Quaternary ammonium compound type muscle relaxant
DG00768 Suxamethonium
D02275 Suxamethonium chloride hydrate
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (muscle type)
D02275 Suxamethonium chloride hydrate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02275 Suxamethonium chloride hydrate
D02275 Suxamethonium chloride injection
D02275 Suxamethonium chloride for injection
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG00768 Suxamethonium
DG01742 Quaternary ammonium compound type muscle relaxant
DG00768 Suxamethonium
|
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| Other DBs |
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| KCF data |
ATOM 24
1 O0 O 36.1482 -17.7472
2 N1d N 17.1667 -17.6692 #+
3 C1b C 18.3814 -18.3641
4 C1b C 19.5960 -17.6633
5 O7a O 20.8048 -18.3524
6 C7a C 22.0193 -17.6576
7 C1b C 23.2341 -18.3467
8 O6a O 22.0835 -16.2502
9 C1b C 24.4426 -17.6459
10 C7a C 25.6573 -18.3407
11 O7a O 26.8661 -17.6400
12 O6a O 25.7156 -19.7422
13 C1b C 28.0807 -18.3350
14 C1b C 29.2954 -17.6342
15 N1d N 30.5099 -18.3350 #+
16 C1a C 31.7231 -19.0355
17 C1a C 31.2106 -17.1209
18 C1a C 29.8105 -19.5468
19 C1a C 15.9535 -16.9688
20 C1a C 16.4754 -18.8721
21 C1a C 17.8716 -16.4430
22 X Cl 29.6335 -15.1291 #-
23 X Cl 16.9274 -14.7027 #-
24 O0 O 36.1482 -17.7472
BOND 19
1 2 3 1
2 3 4 1
3 4 5 1
4 5 6 1
5 6 7 1
6 6 8 2
7 7 9 1
8 9 10 1
9 10 11 1
10 10 12 2
11 11 13 1
12 13 14 1
13 14 15 1
14 15 16 1
15 15 17 1
16 15 18 1
17 2 19 1
18 2 20 1
19 2 21 1
BRACKET 1 34.4400 -18.6900 34.4400 -16.8000
1 36.5400 -16.8000 36.5400 -18.6900
1 2
ORIGINAL 1 1
REPEAT 1 24
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