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KEGG   DRUG: Moxifloxacin hydrochloride
Entry
D00874                      Drug                                   
Name
Moxifloxacin hydrochloride (JAN/USP);
Avelox (TN);
Vigamox (TN)
Product
MOXIFLOXACIN (Fresenius Kabi USA), MOXIFLOXACIN (Hp Halden Pharma AS), VIGAMOX (Harrow Eye), VIGAMOX (Novartis Pharmaceuticals Corporation)
  Generic
MOXIFLOXACIN (A-S Medication Solutions), MOXIFLOXACIN (A-S Medication Solutions), MOXIFLOXACIN (A-S Medication Solutions), MOXIFLOXACIN (Advanced Rx Pharmacy of Tennessee), MOXIFLOXACIN (Aurobindo Pharma Limited), MOXIFLOXACIN (Bryant Ranch Prepack), MOXIFLOXACIN (Camber Pharmaceuticals), MOXIFLOXACIN (Direct Rx), MOXIFLOXACIN (Dr. Reddy's Laboratories Limited), MOXIFLOXACIN (Lupin Pharmaceuticals), MOXIFLOXACIN (Lupin Pharmaceuticals), MOXIFLOXACIN (NorthStar Rx LLC), MOXIFLOXACIN (PD-Rx Pharmaceuticals), MOXIFLOXACIN (Proficient Rx LP), MOXIFLOXACIN (RPK Pharmaceuticals), MOXIFLOXACIN (RedPharm Drug), MOXIFLOXACIN HYDROCHLORIDE (A-S Medication Solutions), MOXIFLOXACIN HYDROCHLORIDE (A-S Medication Solutions), MOXIFLOXACIN HYDROCHLORIDE (A-S Medication Solutions), MOXIFLOXACIN HYDROCHLORIDE (A-S Medication Solutions), MOXIFLOXACIN HYDROCHLORIDE (A-S Medication Solutions), MOXIFLOXACIN HYDROCHLORIDE (American Health Packaging), MOXIFLOXACIN HYDROCHLORIDE (Aurobindo Pharma Limited), MOXIFLOXACIN HYDROCHLORIDE (AvPAK), MOXIFLOXACIN HYDROCHLORIDE (Breckenridge Pharmaceutical), MOXIFLOXACIN HYDROCHLORIDE (Bryant Ranch Prepack), MOXIFLOXACIN HYDROCHLORIDE (Major Pharmaceuticals), MOXIFLOXACIN HYDROCHLORIDE (Mylan Institutional LLC), MOXIFLOXACIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), MOXIFLOXACIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), MOXIFLOXACIN HYDROCHLORIDE (PD-Rx Pharmaceuticals), MOXIFLOXACIN HYDROCHLORIDE (REMEDYREPACK), MOXIFLOXACIN HYDROCHLORIDE (Rising Pharma Holdings), MOXIFLOXACIN HYDROCHLORIDE (Somerset Therapeutics), MOXIFLOXACIN HYDROCHLORIDE (Teva Pharmaceuticals USA), MOXIFLOXACIN HYDROCHLORIDE (Upsher-Smith Laboratories), MOXIFLOXACIN HYDROCHLORIDE TABLETS, 400 MG (MSN LABORATORIES PRIVATE LIMITED), MOXIFLOXACIN HYDROCHLORIDE TABLETS, 400 MG (Novadoz Pharmaceuticals LLC), MOXIFLOXACIN HYDROCHLORIDE TABLETS, 400 MG (PD-Rx Pharmaceuticals), MOXIFLOXACIN OPHTHALMIC (A-S Medication Solutions), MOXIFLOXACIN OPHTHALMIC SOLUTION (A-S Medication Solutions), MOXIFLOXACIN OPHTHALMIC SOLUTION (Alembic Pharmaceuticals Limited), MOXIFLOXACIN OPHTHALMIC SOLUTION (Alembic Pharmaceuticals), MOXIFLOXACIN OPHTHALMIC SOLUTION (Fosun Pharma USA), MOXIFLOXACIN OPHTHALMIC SOLUTION (Gland Pharma Limited), MOXIFLOXACIN OPHTHALMIC SOLUTION (RPK Pharmaceuticals), MOXIFLOXACIN OPHTHALMIC SOLUTION (Sandoz)
Formula
C21H24FN3O4. HCl
Exact mass
437.1518
Mol weight
437.89
Structure
Simcomp
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Remark
Same as: C08054
Therapeutic category: 1319 6241
ATC code: J01MA14 S01AE07
Chemical structure group: DG00626
Product (DG00626): D00874<JP/US> D11618<US>
Efficacy
Antibacterial, Nucleic acid biosynthesis inhibitor
  Disease
Plague [DS:H00297]
Bacterial conjunctivitis [DS:H01366]
Target
DNA gyrase [KO:K02469 K02470]
topoisomerase IV [KO:K02621 K02622]
Interaction
Structure map
map07014  Quinolones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA14 Moxifloxacin
      D00874  Moxifloxacin hydrochloride (JAN/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE07 Moxifloxacin
      D00874  Moxifloxacin hydrochloride (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Moxifloxacin
    D00874  Moxifloxacin hydrochloride (JAN/USP)
 Ophthalmic Agents
  Ophthalmic Anti-Infectives
   Antibacterials, Ophthalmic
    Moxifloxacin
     D00874  Moxifloxacin hydrochloride (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00874  Moxifloxacin hydrochloride (JAN/USP)
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6241  Pyridonecarboxylic acids
     D00874  Moxifloxacin hydrochloride (JAN/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01550  Quinolone
   DG01549  Fluoroquinolone
    DG00626  Moxifloxacin
     D00874  Moxifloxacin hydrochloride
Drug classes [BR:br08332]
 Antibacterial
  DG01549  Fluoroquinolone
   D00874  Moxifloxacin hydrochloride
Antimicrobials [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   Fluoroquinolone
    D00874  Moxifloxacin hydrochloride (JAN/USP) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D00874
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00874
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00874
Drug groups [BR:br08330]
 Antibacterial
  DG01550  Quinolone
   DG01549  Fluoroquinolone
    DG00626  Moxifloxacin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Nucleic acid synthesis inhibitor
   Fluoroquinolone
    DG00626  Moxifloxacin
Other DBs
CAS: 186826-86-8
PubChem: 7847939
ChEBI: 7008
LigandBox: D00874
NIKKAJI: J785.620B
KCF data

ATOM        30
            1   X   Cl   24.1157  -18.4050
            2   C8y C    18.9037  -16.3042
            3   N4y N    20.1198  -16.9999
            4   C8y C    17.6936  -17.0058
            5   C8y C    18.8979  -14.9068
            6   C1y C    20.1081  -18.4031
            7   C8x C    21.3241  -16.2925
            8   C8y C    16.4834  -16.3042
            9   O2a O    17.6819  -18.4031
            10  C8y C    20.1081  -14.1995
            11  C8x C    17.6936  -14.2053
            12  C1x C    20.7980  -19.6191
            13  C1x C    19.3949  -19.6016
            14  C8y C    21.3184  -14.8951
            15  N1y N    15.2966  -17.1988
            16  C8y C    16.4834  -14.9068
            17  C1a C    16.4658  -19.1047
            18  O5x O    20.0905  -12.8080
            19  C6a C    22.5227  -14.1995
            20  C1x C    14.4604  -16.0703
            21  C1x C    14.4838  -18.3388
            22  X   F    15.2672  -14.2112
            23  O6a O    23.7271  -14.9068
            24  O6a O    22.5169  -12.8023
            25  C1y C    13.1332  -16.5206
            26  C1y C    13.1449  -17.9119
            27  C1x C    11.9230  -15.8307
            28  N1x N    11.9464  -18.6135
            29  C1x C    10.7245  -16.5380
            30  C1x C    10.7362  -17.9295
BOND        33
            1     2   3 1
            2     2   4 2
            3     2   5 1
            4     3   6 1
            5     3   7 1
            6     4   8 1
            7     4   9 1
            8     5  10 1
            9     5  11 2
            10    6  12 1
            11    6  13 1
            12    7  14 2
            13    8  15 1
            14    8  16 2
            15    9  17 1
            16   10  18 2
            17   14  19 1
            18   15  20 1
            19   15  21 1
            20   16  22 1
            21   19  23 1
            22   19  24 2
            23   20  25 1
            24   21  26 1
            25   25  27 1
            26   26  28 1
            27   27  29 1
            28   28  30 1
            29   10  14 1
            30   11  16 1
            31   12  13 1
            32   25  26 1
            33   29  30 1

» Japanese version   » Back

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Ontology (9)   
   KEGG BRITE (9)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (3)   
Drug (3)   
   KEGG DGROUP (1)   
   LigandBox (1)   
   SIDER (1)   
Chemical substance (4)   
   KEGG COMPOUND (1)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
Gene (4)   
   KEGG ORTHOLOGY (4)   
All databases (24)   

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