| Entry |
|
|---|
| Name |
Nizatidine (JP18/USP/INN);
Acinon (TN);
Axid (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C12H21N5O2S2
|
|---|
| Exact mass |
331.1137
|
|---|
| Mol weight |
331.46
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
|
|---|
| Remark |
| Therapeutic category: | 2325 |
|
|---|
| Efficacy |
Anti-ulcerative, H2 receptor antagonist |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07227 | Histamine H2/H3 receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BA H2-receptor antagonists
A02BA04 Nizatidine
D00440 Nizatidine (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Gastrointestinal Agents
Histamine2 (H2) Receptor Antagonists
Nizatidine
D00440 Nizatidine (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
23 Digestive organ agents
232 Peptic ulcer agents
2325 H2 blockers
D00440 Nizatidine (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for digestive organs
09 Histamine H2 receptor blocker containing drugs
D00440 Nizatidine (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Nizatidine
D00440 Nizatidine (JP18/USP/INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
D00440 Nizatidine
Drug classes [BR:br08332]
Gastrointestinal agent
DG01481 Histamine receptor H2 antagonist
D00440 Nizatidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH2
D00440 Nizatidine (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00440 Nizatidine
D00440 Nizatidine capsules
Rx-to-OTC switch list in the USA [br08315.html]
D00440
Rx-to-OTC switch list in Japan [br08314.html]
D00440
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C1b C 21.6127 -25.2508
2 S2a S 22.8717 -24.5514
3 C1b C 24.0608 -25.2508
4 C1b C 25.2498 -24.5514
5 N1b N 26.5088 -25.2508
6 C2c C 27.6979 -24.5514
7 C8y C 20.4236 -24.5514
8 N5x N 20.4236 -23.1525
9 C8y C 19.0946 -22.7328
10 S2x S 18.2553 -23.8519
11 C8x C 19.0946 -24.9710
12 C1b C 18.6750 -21.4038
13 C2b C 28.9569 -25.2508
14 N1c N 17.3091 -21.1017
15 C1a C 16.3385 -22.1622
16 C1a C 16.8910 -19.7792
17 N2b N 30.1567 -24.5315 #+
18 O3a O 31.3796 -25.2108
19 O3a O 30.1338 -23.1526 #-
20 N1b N 27.7512 -23.1705
21 C1a C 26.5443 -22.4100
BOND 21
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 7 1
7 7 8 1
8 8 9 2
9 9 10 1
10 10 11 1
11 7 11 2
12 9 12 1
13 6 13 2
14 12 14 1
15 14 15 1
16 14 16 1
17 13 17 1
18 17 18 2
19 17 19 1
20 6 20 1
21 20 21 1
|
|---|