KEGG NETWORK: N01824

NETWORK: N01824

Entry

N01824                      Network

Name

SGK1-NHERF1+NPT signaling pathway

Definition

SGK1 -> (NHERF1+NPT) -> (Na+,Pi)(cyto)

Expanded

6446 -> (9368+6569+10568+142680) -> (C01330,C00009)

Class

nt06325 Hormone/cytokine signaling

Type

Reference

Pathway

hsa04928

Parathyroid hormone synthesis, secretion and action

Gene

6446	SGK1; serum/glucocorticoid regulated kinase 1

9368	NHERF1; NHERF family PDZ scaffold protein 1

6569	SLC34A1; solute carrier family 34 member 1

10568

SLC34A2; solute carrier family 34 member 2

142680

SLC34A3; solute carrier family 34 member 3

Metabolite

C01330

Sodium cation

C00009

Orthophosphate

Reference

PMID:27498418

Authors

Andrukhova O, Streicher C, Zeitz U, Erben RG

Title

Fgf23 and parathyroid hormone signaling interact in kidney and bone.

Journal

Mol Cell Endocrinol 436:224-39 (2016)
DOI:10.1016/j.mce.2016.07.035

Reference

PMID:32982979

Authors

Agoro R, Ni P, Noonan ML, White KE

Title

Osteocytic FGF23 and Its Kidney Function.

Journal

Front Endocrinol (Lausanne) 11:592 (2020)
DOI:10.3389/fendo.2020.00592

Reference

PMID:27622885

Authors

Erben RG, Andrukhova O

Title

FGF23-Klotho signaling axis in the kidney.

Journal

Bone 100:62-68 (2017)
DOI:10.1016/j.bone.2016.09.010

Reference

PMID:30217676

Authors

Takashi Y, Fukumoto S

Title

FGF23 beyond Phosphotropic Hormone.

Journal

Trends Endocrinol Metab 29:755-767 (2018)
DOI:10.1016/j.tem.2018.08.006

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Gene (5)   
   KEGG GENES (5)   
Literature (4)   
   PubMed (4)   
All databases (12)   

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