KEGG NETWORK: N01458

NETWORK: N01458

Entry

N01458                      Network

Name

BMP-HAMP signaling pathway

Definition

BMP2/6 -> ((ACVR2B,BMPR2)+(ACVR1,BMPR1A) -> (SMAD1,SMAD5,SMAD9) == SMAD4 => HAMP

Expanded

(650,654) -> ((93,659)+(90,657) -> (4086,4090,4093) == 4089 => 57817

Class

nt06507 TGFB signaling

Type

Reference

Pathway

TGF-beta signaling pathway

Gene

650	BMP2; bone morphogenetic protein 2

654	BMP6; bone morphogenetic protein 6

93	ACVR2B; activin A receptor type 2B

659	BMPR2; bone morphogenetic protein receptor type 2

90	ACVR1; activin A receptor type 1

657	BMPR1A; bone morphogenetic protein receptor type 1A

4086	SMAD1; SMAD family member 1

4090	SMAD5; SMAD family member 5

4093	SMAD9; SMAD family member 9

4089	SMAD4; SMAD family member 4

HAMP; hepcidin antimicrobial peptide

Reference

Authors

Pantopoulos K

Title

Inherited Disorders of Iron Overload.

Journal

Front Nutr 5:103 (2018)
DOI:10.3389/fnut.2018.00103

Reference

Authors

Piperno A, Pelucchi S, Mariani R

Title

Inherited iron overload disorders.

Journal

Transl Gastroenterol Hepatol 5:25 (2020)
DOI:10.21037/tgh.2019.11.15

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Gene (11)   
   KEGG GENES (11)   
Literature (2)   
   PubMed (2)   
All databases (14)   

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