KEGG NETWORK: N01457

NETWORK: N01457

Entry

N01457                      Network

Name

Myostatin signaling pathway

Definition

MSTN -> (ACVR2B+(ACVR1B,TGFBR1)) -> (SMAD1,SMAD5,SMAD9) == SMAD4

Expanded

2660 -> (93+(91,7046)) -> (4086,4090,4093) == 4089

Class

nt06507 TGFB signaling

Type

Reference

Pathway

TGF-beta signaling pathway

Cytokine-cytokine receptor interaction

Gene

2660	MSTN; myostatin

93	ACVR2B; activin A receptor type 2B

91	ACVR1B; activin A receptor type 1B

7046	TGFBR1; transforming growth factor beta receptor 1

4086	SMAD1; SMAD family member 1

4090	SMAD5; SMAD family member 5

4093	SMAD9; SMAD family member 9

4089	SMAD4; SMAD family member 4

Reference

Authors

Seeger P, Musso T, Sozzani S

Title

The TGF-beta superfamily in dendritic cell biology.

Journal

Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:10.1016/j.cytogfr.2015.06.002

Reference

Authors

Wakefield LM, Hill CS

Title

Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.

Journal

Nat Rev Cancer 13:328-41 (2013)
DOI:10.1038/nrc3500

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Gene (8)   
   KEGG GENES (8)   
Literature (2)   
   PubMed (2)   
All databases (12)   

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