KEGG NETWORK: N01015

NETWORK: N01015

Entry

N01015                      Network

Name

ATF6-mediated transcription

Definition

ATF6 => (DDIT3,XBP1,HSPA5)

Expanded

22926 => (1649,7494,3309)

Class

nt06534 Unfolded protein response
nt06460 Alzheimer disease
nt06463 Parkinson disease
nt06464 Amyotrophic lateral sclerosis
nt06466 Pathways of neurodegeneration

Type

Reference

Pathway

hsa04141

Protein processing in endoplasmic reticulum

Gene

22926

ATF6; activating transcription factor 6

1649	DDIT3; DNA damage inducible transcript 3

7494	XBP1; X-box binding protein 1

3309	HSPA5; heat shock protein family A (Hsp70) member 5

Reference

PMID:22116877

Authors

Walter P, Ron D

Title

The unfolded protein response: from stress pathway to homeostatic regulation.

Journal

Science 334:1081-6 (2011)
DOI:10.1126/science.1209038

Reference

PMID:19043451

Authors

Kim I, Xu W, Reed JC

Title

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities.

Journal

Nat Rev Drug Discov 7:1013-30 (2008)
DOI:10.1038/nrd2755

Reference

PMID:24027531

Authors

Deldicque L

Title

Endoplasmic reticulum stress in human skeletal muscle: any contribution to sarcopenia?

Journal

Front Physiol 4:236 (2013)
DOI:10.3389/fphys.2013.00236

Reference

PMID:22195283

Authors

Basseri S, Austin RC

Title

Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential.

Journal

Biochem Res Int 2012:841362 (2012)
DOI:10.1155/2012/841362

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Gene (4)   
   KEGG GENES (4)   
Literature (4)   
   PubMed (4)   
All databases (9)   

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