KEGG NETWORK: N00432

NETWORK: N00432

Entry

N00432                      Network

Name

HIV gp120 to CXCR4-GNAQ-PLCB/G-calcineurin

Definition

Env -> (CXCR4,CCR5) -> GNAQ

Expanded

K19287 -> (7852,1234) -> 2776

Class

nt06533 Chemokine signaling
nt06161 Human immunodeficiency virus 1 (HIV-1)

Type

Pathogen

Pathway

hsa05170

Human immunodeficiency virus 1 infection

Disease

H01563

HIV infection

Gene

7852	CXCR4; C-X-C motif chemokine receptor 4

1234	CCR5; C-C motif chemokine receptor 5 (gene/pseudogene)

2776	GNAQ; G protein subunit alpha q

Perturbant

K19287 (Env)

gp160; HIV-1 envelope glycoprotein gp160

Reference

PMID:20041213

Authors

Wu Y, Yoder A

Title

Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.

Journal

PLoS Pathog 5:e1000520 (2009)
DOI:10.1371/journal.ppat.1000520

Reference

PMID:22749173

Authors

Evans VA, Khoury G, Saleh S, Cameron PU, Lewin SR

Title

HIV persistence: chemokines and their signalling pathways.

Journal

Cytokine Growth Factor Rev 23:151-7 (2012)
DOI:10.1016/j.cytogfr.2012.05.002

Reference

PMID:23806647

Authors

Abbas W, Herbein G

Title

Plasma membrane signaling in HIV-1 infection.

Journal

Biochim Biophys Acta 1838:1132-42 (2014)
DOI:10.1016/j.bbamem.2013.06.020

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (3)   
Literature (3)   
   PubMed (3)   
All databases (8)   

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