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Ontology

KEGG BRITE

pdic00001            KEGG Orthology (KO) 
pdic01000            Enzymes 


Pathway

KEGG PATHWAY

pdic00061            Fatty acid biosynthesis - Phyllostomus discolor (pale spear-nosed bat) 
pdic00620            Pyruvate metabolism - Phyllostomus discolor (pale spear-nosed bat) 
pdic00640            Propanoate metabolism - Phyllostomus discolor (pale spear-nosed bat) 
pdic01100            Metabolic pathways - Phyllostomus discolor (pale spear-nosed bat) 
pdic01212            Fatty acid metabolism - Phyllostomus discolor (pale spear-nosed bat) 
pdic04152            AMPK signaling pathway - Phyllostomus discolor (pale spear-nosed bat) 
pdic04910            Insulin signaling pathway - Phyllostomus discolor (pale spear-nosed bat) 
pdic04922            Glucagon signaling pathway - Phyllostomus discolor (pale spear-nosed bat) 
pdic04936            Alcoholic liver disease - Phyllostomus discolor (pale spear-nosed bat) 

KEGG MODULE

pdic_M00082            
pdic_M00874            


Chemical substance

KEGG COMPOUND

C00002               ATP; Adenosine 5'-triphosphate 
C00008               ADP; Adenosine 5'-diphosphate 
C00009               Orthophosphate; Phosphate; Phosphoric acid; Orthophosphoric acid 
C00024               Acetyl-CoA; Acetyl coenzyme A 
C00083               Malonyl-CoA; Malonyl coenzyme A 
C00288               HCO3-; Hydrogencarbonate; Bicarbonate; Hydrogen carbonate; Acid carbonate 
C04419               Carboxybiotin-carboxyl-carrier protein; [Biotin carboxyl-carrier protein]-carboxybiotin-N6-L-lysine; 
C06250               Holo-[carboxylase]; Biotin-carboxyl-carrier protein; [Biotin carboxyl-carrier protein]-biotin-N6-L-l 


Chemical reaction

KEGG ENZYME

2.1.3.15             acetyl-CoA carboxytransferase; accAD (gene names) 
6.3.4.14             biotin carboxylase; accC (gene name); biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-for 
6.4.1.2              acetyl-CoA carboxylase; HFA1 (gene name); ACC1 (gene name); acetyl coenzyme A carboxylase; acetyl-Co 

KEGG REACTION

R00742               acetyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate +  
R04385               biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming); ATP + Holo-[carboxylase] + HCO3 
R04386               carboxybiotin-carboxyl-carrier-protein:acetyl-CoA carboxytransferase; Acetyl-CoA + Carboxybiotin-car 


Genome

KEGG GENOME

T07739               pdic; Phyllostomus discolor (pale spear-nosed bat) 


Gene

KEGG ORTHOLOGY

K11262               ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] 

NCBI-PROTEINID

XP_028375893           

NCBI-Gene

114502852            ACACA; acetyl-CoA carboxylase alpha 


Protein sequence

UniProt

A0A6J2MCN8           [A0A6J2MCN8] RecName: Full=Acetyl-CoA carboxylase 1 {ECO:0000256|ARBA:ARBA00020135}; EC=6.4.1.2 {ECO 

RefSeq(pep)

XP_028375893         acetyl-CoA carboxylase 1 isoform X3 [Phyllostomus discolor]. 
XP_028375894         acetyl-CoA carboxylase 1 isoform X2 [Phyllostomus discolor]. 
XP_035889512         acetyl-CoA carboxylase 1 isoform X1 [Phyllostomus discolor]. 
XP_035889513         acetyl-CoA carboxylase 1 isoform X2 [Phyllostomus discolor]. 
XP_035889514         acetyl-CoA carboxylase 1 isoform X2 [Phyllostomus discolor]. 
XP_035889515         acetyl-CoA carboxylase 1 isoform X2 [Phyllostomus discolor]. 
XP_035889516         acetyl-CoA carboxylase 1 isoform X4 [Phyllostomus discolor]. 


DNA sequence

RefSeq(nuc)

XM_028520092         PREDICTED: Phyllostomus discolor acetyl-CoA carboxylase alpha (ACACA), transcript variant X4, mRNA. 
XM_028520093         PREDICTED: Phyllostomus discolor acetyl-CoA carboxylase alpha (ACACA), transcript variant X2, mRNA. 
XM_036033619         PREDICTED: Phyllostomus discolor acetyl-CoA carboxylase alpha (ACACA), transcript variant X1, mRNA. 
XM_036033620         PREDICTED: Phyllostomus discolor acetyl-CoA carboxylase alpha (ACACA), transcript variant X3, mRNA. 
XM_036033621         PREDICTED: Phyllostomus discolor acetyl-CoA carboxylase alpha (ACACA), transcript variant X5, mRNA. 
XM_036033622         PREDICTED: Phyllostomus discolor acetyl-CoA carboxylase alpha (ACACA), transcript variant X6, mRNA. 
XM_036033623         PREDICTED: Phyllostomus discolor acetyl-CoA carboxylase alpha (ACACA), transcript variant X7, mRNA. 


Protein domain

Pfam

PF00289              Biotin carboxylase, N-terminal domain 
PF00364              Biotin-requiring enzyme 
PF01039              Carboxyl transferase domain 
PF02222              ATP-grasp domain 
PF02655              ATP-grasp domain 
PF02785              Biotin carboxylase C-terminal domain 
PF02786              Carbamoyl-phosphate synthase L chain, ATP binding domain 
PF07478              D-ala D-ala ligase C-terminus 
PF08326              Acetyl-CoA carboxylase, central region 
PF16371              N terminal of Calcineurin-like phosphoesterase 
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