Last updated: 3/5/2016
Pitchers
| Position | Name | Number | Acquired |
| LHP | Matt Boyd | 48 | 2015 - Trade with Toronto Blue Jays |
| RHP | Buck Farmer | 45 | 2013 - Draft (156th overall pick) |
| RHP | Jeff Ferrell | 26 | 2010 - Draft (793rd overall pick) |
| RHP | Michael Fulmer | 32 | 2015 - Trade with New York Mets |
| RHP | Shane Greene | 61 | 2014 - Trade with New York Yankees |
| LHP | Blaine Hardy | 65 | 2013 - Free agent signing (minor) |
| LHP | Jairo Labourt | 53 | 2015 - Trade with Toronto Blue Jays |
| RHP | Mark Lowe | 21 | 2015 - Free agent signing |
| RHP | Angel Nesbitt | 60 | 2008 - Free agent signing (amateur) |
| LHP | Daniel Norris | 44 | 2015 - Trade with Toronto Blue Jays |
| RHP | Mike Pelfrey | 37 | 2015 - Free agent signing |
| RHP | Montreal Robertson | 40 | 2011 - Draft (887th overall pick) |
| RHP | Francisco Rodriguez | 57 | 2015 - Trade with Milwaukee Brewers |
| RHP | Bruce Rondon | 43 | 2007 - Free agent signing (amateur) |
| LHP | Kyle Ryan | 56 | 2010 - Draft (373rd overall pick) |
| RHP | Anibal Sanchez | 19 | 2012 - Trade with Florida Marlins |
| RHP | Jose Valdez | 58 | 2009 - Free agent signing (amateur) |
| RHP | Drew VerHagen | 64 | 2012 - Draft (154th overall pick) |
| RHP | Justin Verlander | 35 | 2004 - Draft (2nd overall pick) |
| RHP | Alex Wilson | 30 | 2014 - Trade with Boston Red Sox |
| LHP | Justin Wilson | 38 | 2015 - Trade with New York Yankees |
| RHP | Jordan Zimmermann | 27 | 2015 - Free agent signing |
Catchers
| Bat/Throw | Player | Number | Acquired |
| R/R | Bryan Holaday | 50 | 2010 - Draft (193rd overall pick) |
| R/R | James McCann | 34 | 2011 - Draft (76th overall pick) |
| S/R | Jarrod Saltalamacchia | 39 | 2015 - Free agent signing |
Infielders
| Bat/Throw | Player | Number | Acquired |
| R/R | Mike Aviles | 14 | 2015 - Free agent signing |
| R/R | Miguel Cabrera | 24 | 2007 - Trade with Florida Marlins |
| R/R | Nick Castellanos | 9 | 2010 - Draft (44th overall pick) |
| R/R | Jose Iglesias | 1 | 2013 - Trade with Boston Red Sox |
| R/R | Ian Kinsler | 3 | 2013 - Trade with Texas Rangers |
| R/R | Dixon Machado | 49 | 2008 - Free agent signing (amateur) |
| S/R | Victor Martinez | 41 | 2010 - Free agent signing |
| S/R | Andrew Romine | 27 | 2014 - Trade with Los Angeles Angels |
Outfielders
| Bat/Throw | Player | Number | Acquired |
| R/R | Wynton Bernard | 63 | 2014 - Free agent signing (minor) |
| L/L | Tyler Collins | 18 | 2011 - Draft (197th overall pick) |
| L/L | Anthony Gose | 12 | 2014 - Trade with Toronto Blue Jays |
| R/R | J.D. Martinez | 28 | 2014 - Free agent signing (minor) |
| R/R | Cameron Maybin | 4 | 2015 - Trade with Atlanta Braves |
| L/R | Steven Moya | 33 | 2008 - Free agent signing (amateur) |
| R/R | Justin Upton | 8 | 2016 - Free agent signing |
Notes
Amateur free agents are internationally signed free agents, as the First-Year Player Draft only applies to players from Canada and the USA or its possessions (for example, Puerto Rico)
Minor league free agents are players who were signed to minor league contracts after being released by another organization