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PAnG: finding patterns in annotation graphs

Published: 20 May 2012 Publication History

Abstract

Annotation graph datasets are a natural representation of scientific knowledge. They are common in the life sciences and health sciences, where concepts such as genes, proteins or clinical trials are annotated with controlled vocabulary terms from ontologies. We present a tool, PAnG (Patterns in Annotation Graphs), that is based on a complementary methodology of graph summarization and dense subgraphs. The elements of a graph summary correspond to a pattern and its visualization can provide an explanation of the underlying knowledge. Scientists can use PAnG to develop hypotheses and for exploration.

References

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PAnG. http://pang.umiacs.umd.edu.
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M. Acosta, M.-E. Vidal, T. Lampo, J. Castillo, and E. Ruckhaus. Anapsid: An adaptive query processing engine for sparql endpoints. In Proc. of International Semantic Web Conference (ISWC), 2011.
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O. Hassanzadeh, A. Kementsietsidis, L. Lim, R. J. Miller, and M. Wang. Linkedct: A linked data space for clinical trials. In Proc. WWW 2009 Workshop on Linked Data on the Web (LDOW2009), 2009.
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B. Kang, N. Grancher, V. Koyffmann, D. Lardemer, S. Burney, and M. Ahmad. Multiple interactions between cryptochrome and phototropin blue-light signalling pathways in arabidopsis thaliana. Planta, 227(5):1091--1099, 2008.
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S. Navlakha, R. Rastogi, and N. Shrivastava. Graph summarization with bounded error. In Proc. of Conference on Management of Data (SIGMOD), 2008.
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M. Ohgishi, K. Saji£, K. Okada, and T. Sakai. Functional analysis of each blue light receptor, cry1, cry2, phot1, and phot2, by using combinatorial multiple mutants in arabidopsis. Proc. of the National Academy of Sciences, 1010(8):2223--2228, 2004.
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B. Saha, A. Hoch, S. Khuller, L. Raschid, and X.-N. Zhang. Dense subgraphs with restrictions and applications to gene annotation graphs. In Conference on Research on Computational Molecular Biology (RECOMB), 2010.
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Cited By

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  • (2015)ALIDProceedings of the VLDB Endowment10.14778/2757807.27578088:8(826-837)Online publication date: 1-Apr-2015
  • (2015)Automatic Curation of Clinical Trials Data in LinkedCTThe Semantic Web - ISWC 201510.1007/978-3-319-25010-6_16(270-278)Online publication date: 24-Oct-2015
  • (2015)Demonstration: Mining Sentence and Annotation Evidence for a Cross Genome Study of the Plant Hormone EthyleneData Integration in the Life Sciences10.1007/978-3-319-21843-4_20(251-255)Online publication date: 8-Jul-2015
  • Show More Cited By

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Published In

cover image ACM Conferences
SIGMOD '12: Proceedings of the 2012 ACM SIGMOD International Conference on Management of Data
May 2012
886 pages
ISBN:9781450312479
DOI:10.1145/2213836
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Association for Computing Machinery

New York, NY, United States

Publication History

Published: 20 May 2012

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Author Tags

  1. dense subgraphs
  2. graph summarization
  3. link prediction

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SIGMOD/PODS '12
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SIGMOD '12 Paper Acceptance Rate 48 of 289 submissions, 17%;
Overall Acceptance Rate 785 of 4,003 submissions, 20%

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Cited By

View all
  • (2015)ALIDProceedings of the VLDB Endowment10.14778/2757807.27578088:8(826-837)Online publication date: 1-Apr-2015
  • (2015)Automatic Curation of Clinical Trials Data in LinkedCTThe Semantic Web - ISWC 201510.1007/978-3-319-25010-6_16(270-278)Online publication date: 24-Oct-2015
  • (2015)Demonstration: Mining Sentence and Annotation Evidence for a Cross Genome Study of the Plant Hormone EthyleneData Integration in the Life Sciences10.1007/978-3-319-21843-4_20(251-255)Online publication date: 8-Jul-2015
  • (2015)Combining Multiple Knowledge Sources: A Case Study of Drug Induced Liver InjuryData Integration in the Life Sciences10.1007/978-3-319-21843-4_1(3-12)Online publication date: 8-Jul-2015
  • (2012)Finding cross genome patterns in annotation graphsProceedings of the 8th international conference on Data Integration in the Life Sciences10.1007/978-3-642-31040-9_3(21-36)Online publication date: 28-Jun-2012

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