Tracking a Global Threat: a New Genotyping Method for Candida auris

mBio. 2020 Mar 10;11(2):e00259-20. doi: 10.1128/mBio.00259-20.

Authors

Christina A Cuomo¹, Alexandre Alanio^{2

3

4

5}

Affiliations

¹ Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA cuomo@broadinstitute.org.
² Institut Pasteur, Molecular Mycology Unit, CNRS UMR2000, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Paris, France.
³ Laboratoire de Parasitologie-Mycologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
⁴ Groupe Hospitalier Saint-Louis Lariboisière Fernand-Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
⁵ Université de Paris, Paris, France.

Abstract

Over the past decade, Candida auris has emerged as an urgent threat to public health. Initially reported from cases of ear infections in Japan and Korea, C. auris has since been detected around the world. While whole-genome sequencing has been extensively used to trace the genetic relationships of the global emergence and local outbreaks, a recent report in mBio describes a targeted genotyping method as a rapid and inexpensive method for classifying C. auris isolates (T. de Groot, Y. Puts, I. Berrio, A. Chowdhary, and J. F. Meis, mBio 11:e02971-19, https://doi.org/10.1128/mBio.02971-19, 2020).

Keywords: Candida auris; genome analysis; genotyping; short tandem repeats.

Publication types

Comment

MeSH terms

Antifungal Agents
Candida / genetics*
Candidiasis*
Genotype
Humans
Microsatellite Repeats
Republic of Korea

Substances

Antifungal Agents