Abstract
Nine of 11 patients with hepatoblastoma treated with cisplatin (DDP) based chemotherapy had a complete (CR) or partial (PR) remission. Five of these patients had measurable pulmonary disease and four achieved a CR of pulmonary lesions. The average interval of disease control following DDP was three times that of Adriamycin (ADR). DDP is an effective agent in the treatment of hepatoblastoma.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / adverse effects
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Carcinoma, Hepatocellular / drug therapy*
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Child, Preschool
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Cisplatin / administration & dosage
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Cisplatin / adverse effects
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Female
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Fluorouracil / administration & dosage
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Humans
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Infant
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Liver Neoplasms / drug therapy*
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Male
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Prognosis
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Vincristine / administration & dosage
Substances
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Vincristine
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Cisplatin
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Fluorouracil