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0.5 billion events per second time correlated single photon counting using CMOS SPAD arrays

Opt Lett. 2015 Sep 15;40(18):4305-8. doi: 10.1364/OL.40.004305.

Abstract

We present a digital architecture for fast acquisition of time correlated single photon counting (TCSPC) events from a 32×32 complementary metal oxide semiconductor (CMOS) single photon avalanche detector (SPAD) array (Megaframe) to the computer memory. Custom firmware was written to transmit event codes from 1024-TCSPC-enabled pixels for fast transfer of TCSPC events. Our 1024-channel TCSPC system is capable of acquiring up to 0.5×10(9) TCSPC events per second with 16 histogram bins spanning a 14 ns width. Other options include 320×10(6) TCSPC events per second with 256 histogram bins spanning either a 14 or 56 ns time window. We present a wide-field fluorescence microscopy setup demonstrating fast fluorescence lifetime data acquisition. To the best of our knowledge, this is the fastest direct TCSPC transfer from a single photon counting device to the computer to date.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Convallaria
  • Metals / chemistry
  • Optical Devices*
  • Optical Imaging
  • Oxides / chemistry
  • Photons*
  • Semiconductors
  • Time Factors

Substances

  • Metals
  • Oxides