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Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

Chem Rev. 2015 Oct 14;115(19):11043-78. doi: 10.1021/cr5006793. Epub 2015 Apr 15.

Authors

Ulrich Lächelt^{1

2}, Ernst Wagner^{1

2}

Affiliations

¹ Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig Maximilians Universität , 81377 Munich, Germany.
² Nanosystems Initiative Munich (NIM), 80799 Munich, Germany.

PMID: 25872804
DOI: 10.1021/cr5006793

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Drug Delivery Systems
Genetic Therapy*
Humans
Nucleic Acids / chemistry
Nucleic Acids / genetics
Nucleic Acids / therapeutic use*
Polymers / chemistry
Polymers / therapeutic use*

Substances

Nucleic Acids
Polymers