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Merkel cell polyomavirus DNA in persons without merkel cell carcinoma

Emerg Infect Dis. 2009 Sep;15(9):1496-8. doi: 10.3201/eid1509.081575.

Abstract

Merkel cell polyomavirus (MCPyV) DNA was detected in 88% of Merkel cell carcinomas in contrast to 16% of other skin tumors. MCPyV was also found in anogenital and oral samples (31%) and eyebrow hairs (50%) of HIV-positive men and in forehead swabs (62%) of healthy controls. MCPyV thus appears to be widespread.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinoma, Merkel Cell / virology*
  • DNA, Viral / analysis
  • DNA, Viral / isolation & purification*
  • Eyebrows / virology*
  • Forehead / virology
  • Genitalia, Male / virology
  • HIV Seropositivity
  • Humans
  • Male
  • Mouth / virology
  • Polyomavirus / genetics
  • Polyomavirus / isolation & purification*
  • Polyomavirus Infections / virology*
  • Skin / virology*
  • Tumor Virus Infections / virology*

Substances

  • DNA, Viral