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Diagnostic difficulties in the interpretation of fine needle aspirates of salivary gland lesions: the problem revisited

Cytopathology. 1995 Oct;6(5):285-300. doi: 10.1111/j.1365-2303.1995.tb00574.x.

Abstract

Cases of salivary gland lesions (n = 325), mainly neoplastic but including a small number of non-neoplastic lesions, investigated by fine needle aspiration (FNA) and with histological correlation, are reviewed. The review identified a number of differential diagnostic problems which are discussed in some detail. One false-positive and eight false-negative diagnoses had been made resulting in a 99.5% specificity and a 85.5% sensitivity. If type-specific diagnoses are made only when all defined diagnostic criteria are present and if any uncertainty is clearly conveyed to the clinician, FNA is a safe and accurate tool in the investigation of salivary gland lesions.

Publication types

  • Review

MeSH terms

  • Biopsy, Needle
  • Diagnosis, Differential
  • Humans
  • Salivary Gland Diseases / diagnosis
  • Salivary Gland Diseases / pathology*
  • Salivary Gland Neoplasms / diagnosis
  • Salivary Gland Neoplasms / pathology*