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VWA8 von Willebrand factor A domain containing 8 [ Canis lupus familiaris (dog) ]

Gene ID: 485463, updated on 17-Aug-2024

Summary

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Official Symbol
VWA8provided by VGNC
Official Full Name
von Willebrand factor A domain containing 8provided by VGNC
Primary source
VGNC:VGNC:48325
See related
Ensembl:ENSCAFG00845011611
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See VWA8 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
46
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 22 NC_051826.1 (9025235..9379824)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 22 NC_006604.4 (8793300..9146711)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 22 NC_049243.1 (8780057..9133927)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 22 NC_049282.1 (8717913..9072245)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 22 NC_049763.1 (8768009..9122199)

Chromosome 22 - NC_051826.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119865126 Neighboring gene dnaJ homolog subfamily B member 6-like Neighboring gene uncharacterized LOC102152721 Neighboring gene uncharacterized LOC119865191 Neighboring gene small nucleolar RNA U3 Neighboring gene regulator of cell cycle

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • KIAA0564

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
von Willebrand factor A domain-containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051826.1 Reference ROS_Cfam_1.0

    Range
    9025235..9379824
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038431071.1 → XP_038286999.1  von Willebrand factor A domain-containing protein 8

    UniProtKB/TrEMBL
    A0A8C0T999
    Related
    ENSCAFP00845016401.1, ENSCAFT00845020883.1
    Conserved Domains (4) summary
    COG5271
    Location:107 → 845
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    cd01455
    Location:1712 → 1901
    vWA_F11C1-5a_type; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07728
    Location:104 → 260
    AAA_5; AAA domain (dynein-related subfamily)
    cl38936
    Location:441 → 584
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_005299305.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049282.1 Alternate UMICH_Zoey_3.1

    Range
    8717913..9072245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038506450.1 → XP_038362378.1  von Willebrand factor A domain-containing protein 8

    Conserved Domains (4) summary
    COG5271
    Location:107 → 845
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    cd01455
    Location:1712 → 1901
    vWA_F11C1-5a_type; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07728
    Location:104 → 260
    AAA_5; AAA domain (dynein-related subfamily)
    cl38936
    Location:441 → 584
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_005342415.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049763.1 Alternate UNSW_CanFamBas_1.0

    Range
    8768009..9122199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038633820.1 → XP_038489748.1  von Willebrand factor A domain-containing protein 8

    Conserved Domains (4) summary
    COG5271
    Location:107 → 845
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    cd01455
    Location:1712 → 1901
    vWA_F11C1-5a_type; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07728
    Location:104 → 260
    AAA_5; AAA domain (dynein-related subfamily)
    cl38936
    Location:441 → 584
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_005410197.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049243.1 Alternate UU_Cfam_GSD_1.0

    Range
    8780057..9133927
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038569648.1 → XP_038425576.1  von Willebrand factor A domain-containing protein 8

    UniProtKB/TrEMBL
    A0A8C0T999

RNA

  1. XR_005376290.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006604.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8793300..9146711
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038456847.1 → XP_038312775.1  von Willebrand factor A domain-containing protein 8

    UniProtKB/TrEMBL
    A0A8C0T999
    Conserved Domains (4) summary
    COG5271
    Location:107 → 845
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    cd01455
    Location:1712 → 1901
    vWA_F11C1-5a_type; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    pfam07728
    Location:104 → 260
    AAA_5; AAA domain (dynein-related subfamily)
    cl38936
    Location:441 → 584
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_005313536.1 RNA Sequence

Nucleotide Protein
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