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The trusted data resource for craniofacial researchers worldwide
FaceBase is a collaborative NIDCR-funded project .

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Publications

  1. Quantitative analysis of facial shape in children to support respirator design

    Nemeth, Christopher; Hoskens, Hanne; Wilson, Graham; Jones, Mike; DiPietrantonio, Josef; Salami, Bukola; Harnish, Del; Claes, Peter; Weinberg, Seth M.; Shriver, Mark D.; Hallgrímsson, Benedikt. Applied Ergonomics. vol. 122, 104375. 2025.

    View Abstract View Publication
    The COVID-19 pandemic demonstrated the need for respiratory protection against airborne pathogens. Respirator options for children are limited, and existing designs do not consider differences in facial shape or size. We created a dataset of children’s facial images from three cohorts, then used geometric morphometric analyses of dense and sparse facial landmark representations to quantify age, sex and ancestry-related variation in shape. We found facial shape and size in children vary significantly with age from ages 2 to 18, particularly in dimensions relevant to respirator design. Sex differences are small throughout most of the age range of our sample. Ancestry is associated with significant facial shape variation in dimensions that may affect respirator fit. We offer guidance on how to our results can be used for the appropriate design of devices such as respirators for pediatric populations. We also highlight the need to consider ancestry-related variation in facial morphology to promote equitable, inclusive products.

  2. The ciliary protein C2cd3 is required for mandibular musculoskeletal tissue patterning

    Brooks, Evan C.; Han, Simon J.Y.; Bonatto Paese, Christian Louis; Lewis, Amya A.; Aarnio-Peterson, Megan; Brugmann, Samantha A.. Differentiation. vol. 138, 100782. July 2024.

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  3. Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor

    Guo, Tingwei; Pei, Fei; Zhang, Mingyi; Yamada, Takahiko; Feng, Jifan; Jing, Junjun; Ho, Thach-Vu; Chai, Yang. Cell Stem Cell. vol. 31(6), 904–920.e6. June 2024.

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