… fibrils and amyloid fibrils in tissues has led to the widely held view that the proteinaceous
fibrils … ically and structurally identical to the amyloid fibrils observed in tissues. However, this …

… fibrils, and how mature fibrils are assembled from early fibrils. … the principles for bipolar fibril
assembly were established at … fibrils in tendon and skin and from studies in which fibrils are …

… concentration, (b) fibrils nucleate within these micelles or … fibrils grow by irreversible binding
of monomers to the fibril ends. Simpler, colorimetric methods exist for detecting amyloid fibrils…

… times and faster growth of fibrils. Shorter lag times and faster growth of fibrils were seen at
acidic … lag times and slower growth of fibrils. There was no clear correlation between the rate of …

The formation of nanoscale amyloid fibrils from normally soluble peptides and proteins is a …
, where fibrils may present a catalytic surface for the formation of new aggregates. Fibrils may …

… amyloid fibril species is … fibrils have led to the search for a common fibril formation mechanism.
A full description of this process is essential to our understanding of the link between fibril …

… , such fibrils will be named Type-I-rich fibrils and Type-II-rich fibrils, respectively. Fibril-forming …
Type-I-rich fibrils, whereas Type-II-rich fibrils frequently contain Types IX and XI collagen. …

Amyloid fibrils are ordered aggregates of peptides or proteins that are … fibrils can also be
prepared in vitro and there are three criteria that define a protein aggregate as an amyloid fibril: …

… and FGAIL form fibrils similar to the full-length fibril (24), whereas GAIL does not form fibrils.
Near-UV circular dichroism spectra recorded immediately before insoluble fibrils showed …

… fibrils. The models discussed below are useful in coming to terms with fundamental questions
about amyloid fibrils, such as do fibril… of the conversion from native state to fibril; what is the …