Recent studies have shown that accounting for intraspecific trait variation (ITV) may better
address major questions in community ecology. However, a general picture of the relative …

Abstract The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private–public
partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that …

PURPOSE: Transanal hemorrhoidal dearterialization consists of a Doppler-guided ligation
of the distal branches of the rectal arteries. The aim of this review is to assess the current …

Multiple studies have confirmed the contribution of rare de novo copy number variations to
the risk for autism spectrum disorders,,. But whereas de novo single nucleotide variants …

A major goal in human genetics is to use natural variation to understand the phenotypic
consequences of altering each protein-coding gene in the genome. Here we used exome …

Abstract The Immune Epitope Database (IEDB, iedb. org) captures experimental data
confined in figures, text and tables of the scientific literature, making it freely available and …

The IEDB, www. iedb. org, contains information on immune epitopes—the molecular targets
of adaptive immune responses—curated from the published literature and submitted by …

Estimates from genome-wide association studies (GWAS) of unrelated individuals capture
effects of inherited variation (direct effects), demography (population stratification …

Congenital heart disease (CHD) is the most frequent birth defect, affecting 0.8% of live
births. Many cases occur sporadically and impair reproductive fitness, suggesting a role for …

Risk maps summarizing landscape suitability of novel areas for invading species can be
valuable tools for preventing species' invasions or controlling their spread, but methods …