An efficient system for genetic modification and large-scale cloning of cattle is of importance
for agriculture, biotechnology, and human medicine. Here, actively dividing fetal fibroblasts …

Parthenogenesis is the process by which an egg can develop into an embryo in the absence
of sperm. This process has been characterized to some extent in nonhuman primates (1, 2); …

The successful application of nuclear transfer techniques to a range of mammalian species
has brought the possibility of human therapeutic cloning significantly closer. The objective of …

We have developed a method, using nuclear transplantation, to produce transgenic
embryonic stem (ES)-like cells from fetal bovine fibroblasts. These cells, when reintroduced …

Somatic cell nuclear transfer (SCNT), the technique commonly known as cloning, permits
transformation of a somatic cell into an undifferentiated zygote with the potential to develop …

Somatic cell nuclear transfer (SCNT) technology has recently been used to generate
animals with a common genetic composition. In this study, we report the derivation of a …

Accessibility of human oocytes for research poses a serious ethical challenge to society.
This fact categorically holds true when pursuing some of the most promising areas of …

14 develop abnormally is currently unjustified on scientific grounds and should not be used
by policymakers or other groups as an argument to ban all human cloning research. In our …

The potential of cloning depends in part on whether the procedure can reverse cellular
aging and restore somatic cells to a phenotypically youthful state. Here, we report the birth of …

The neonatal abnormalities, treatments and outcomes in a group of 13 cloned transgenic
calves and fetuses that progressed into the third trimester of pregnancy are described. From …