Fibroproliferative disorders

PB Bitterman, CA Henke - Chest, 1991 - journal.chestnet.org
Fibroproliferative disorders are the leading cause of death in the United States, 1 outstripping
cancer in numeric importance by more than 2: 1. According to vital statistics data published …

Fibroproliferative disorders and their mechanobiology

C Huang, R Ogawa - Connective tissue research, 2012 - Taylor & Francis
Benign and malignant fibroproliferative disorders (FPDs) include idiopathic pulmonary fibrosis,
hepatic cirrhosis, myelofibrosis, systemic sclerosis, Dupuytren’s contracture, hypertrophic …

[HTML][HTML] Macroscopic models for fibroproliferative disorders: A review

L Fusi - Mathematical and Computer Modelling, 2009 - Elsevier
… The paper is structured as follows: after a brief description of wound healing and
fibroproliferative disorders (Section 2) we will present the state of the art of mathematical models for …

Apoptosis in inflammatory–fibroproliferative disorders of the vessel wall

K Walsh, JM Isner - Cardiovascular research, 2000 - academic.oup.com
Apoptotic cell death is a hallmark of inflammatory–fibroproliferative disorders of the vessel
wall. Here, we review what is currently known about cell death within atherosclerotic and …

Fibroproliferative disorders and diabetes: Understanding the pathophysiologic relationship between Peyronie's disease, Dupuytren disease and diabetes

MK Gelbard, J Rosenbloom - Endocrinology, diabetes & …, 2021 - Wiley Online Library
Introduction Fibrosis is characterized by dysregulation and accumulation of extracellular
matrix. Peyronie's disease and Dupuytren disease are fibroproliferative disorders of the tunica …

Lovastatin Induces Fibroblast ApoptosisIn Vitro and In Vivo A Possible Therapy for Fibroproliferative Disorders

A Tan, H Levrey, C Dahm, VA Polunovsky… - American journal of …, 1999 - atsjournals.org
… These findings support further study of 3-hydroxy-3-methylglutaryl–coenzyme A (HMG-CoA)
reductase inhibitors as potential therapy for patients with fibroproliferative disorders. …

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

TA Wynn - The Journal of clinical investigation, 2007 - jci.org
… factors that are involved in mediating fibroproliferation (6), interrupting critical chemokine
signaling pathways could impact the pathogenesis of pulmonary fibroproliferative disorders by …

[HTML][HTML] Comprehensive Ontology of Fibroproliferative Diseases: Protocol for a Semantic Technology Study

M Golec, M Kamdar, S Barteit - JMIR Research Protocols, 2023 - researchprotocols.org
… advances have been made in recent years in understanding the molecular details of fibrosis
[6,7], the causes and potential therapeutic approaches of various fibroproliferative disorders

Apoptosis and cell proliferation markers in inflammatory-fibroproliferative diseases of the vessel wall

EA Klimentova, IA Suchkov, AA Egorov… - Современные …, 2020 - cyberleninka.ru
… Apoptosis is the main feature of inflammatory-fibroproliferative disorders of the vessel wall.
Studies in animal models have shown that smooth muscle cells (SMCs) cultured from …

A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders

R Poon, H Hong, X Wei, J Pan, BA Alman - PLoS One, 2012 - journals.plos.org
Fibroproliferative disorders include neoplastic and reactive processes (eg desmoid tumor …
from β-catenin driven fibroproliferative disorders. Nefopam decreased cell proliferation and β-…