A hundred years after the introduction of aspirin as the first effective anti‐inflammatory drug,
problems of tolerability still beset this class of drugs, in particular, gastrointestinal toxicity. …

… This necessitates the development of COX-II inhibitors that not only … COX-II inhibitors. The
insights from this article could be helpful in seeding the development of next-generation COX-II …

… Cox-II selective NSAIDs have been implicated in increased rates of thrombotic events, mainly
increased myocardial infarction. Evidence comes principally from a study of rofecoxib over …

The mirror neuron (MN) hypothesis of autism has received considerable attention, but to date
has produced inconsistent findings. Using functional MRI, participants with high functioning …

Objectives: Knowledge regarding the incidence and prevalence of acute urinary retention and
the ultimate outcome is very limited. The purpose of the present analysis was to document …

… Meloxicam and rofecoxib exhibit anti-inflammatory and analgesic activity by selective
inhibition of COX-II isoenzyme, which is responsible for the formation of prostaglandins in normal …

Research shows that increased sexual activity is strongly associated with betterhealth
outcomes and greater personal happiness (Karraker, DeLamater, & Schwartz,2011; Lindau & …

… , TNF-α and COX-II were investigated using macrophages in … of iNOS, COX-II and TNF-
α nor protein of COX-II and TNF-α … 13-EB is involved, and COX-II activity is inhibited by 13-MB …

… -2 (COX-II) (Ahmad et al. Citation2012). Our data show over expression of COX-II synthesis,
… Treatment with WRF significantly down-regulated COX-II expression and thus reduced the …

… (COX-II), providing effective analgesia without any effect on platelet function, bleeding time,
or reduced gastrointestinal side effects [3]. The effectiveness of COX-II … of preoperative COX-II …