Department of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, New York (P.C.C., B.S., A.W., S.D.C.); Department of Pharmacology Physiology and Neuroscience, University of South Carolina School of Medicine (S.K.W.) and Dorn VA Medical Center (S.K.W.), Columbia, South Carolina; and Research Triangle Institute, Center for Drug Discovery, Research Triangle Park, North Carolina (S.R.)

Department of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, New York (P.C.C., B.S., A.W., S.D.C.); Department of Pharmacology Physiology and Neuroscience, University of South Carolina School of Medicine (S.K.W.) and Dorn VA Medical Center (S.K.W.), Columbia, South Carolina; and Research Triangle Institute, Center for Drug Discovery, Research Triangle Park, North Carolina (S.R.)

Department of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, New York (P.C.C., B.S., A.W., S.D.C.); Department of Pharmacology Physiology and Neuroscience, University of South Carolina School of Medicine (S.K.W.) and Dorn VA Medical Center (S.K.W.), Columbia, South Carolina; and Research Triangle Institute, Center for Drug Discovery, Research Triangle Park, North Carolina (S.R.)

Department of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, New York (P.C.C., B.S., A.W., S.D.C.); Department of Pharmacology Physiology and Neuroscience, University of South Carolina School of Medicine (S.K.W.) and Dorn VA Medical Center (S.K.W.), Columbia, South Carolina; and Research Triangle Institute, Center for Drug Discovery, Research Triangle Park, North Carolina (S.R.)

Department of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, New York (P.C.C., B.S., A.W., S.D.C.); Department of Pharmacology Physiology and Neuroscience, University of South Carolina School of Medicine (S.K.W.) and Dorn VA Medical Center (S.K.W.), Columbia, South Carolina; and Research Triangle Institute, Center for Drug Discovery, Research Triangle Park, North Carolina (S.R.)

Department of Pharmacology and Toxicology, State University of New York at Buffalo, Buffalo, New York (P.C.C., B.S., A.W., S.D.C.); Department of Pharmacology Physiology and Neuroscience, University of South Carolina School of Medicine (S.K.W.) and Dorn VA Medical Center (S.K.W.), Columbia, South Carolina; and Research Triangle Institute, Center for Drug Discovery, Research Triangle Park, North Carolina (S.R.)