[go: up one dir, main page]
More Web Proxy on the site http://driver.im/ skip to main content
10.5555/827140.827154acmconferencesArticle/Chapter ViewAbstractPublication PagesjcdlConference Proceedingsconference-collections
Article

Protein association discovery in biomedical literature

Published: 27 May 2003 Publication History

Abstract

Protein association discovery can directly contribute toward developing protein pathways; hence it is a significant problem in bioinformatics. LUCAS (Library of User-Oriented Concepts for Access Services) was designed to automatically extract and determine associations among proteins from biomedical literature. Such a tool has notable potential to automate database construction in biomedicine, instead of relying on experts' analysis. This paper reports on the mechanisms for automatically generating clusters of proteins. A formal evaluation of the system, based on a subset of 2000 MEDLINE titles and abstracts, has been conducted against Swiss-Prot database in which the associations among concepts are entered by experts manually.

References

[1]
Berry, M., Dumais, S., and Letsche, T. "Computational methods for intelligent information access". In Proceedings of Supercomputing '95, San Diego, CA, 1995.
[2]
Deerwester, S., Dumais, S. T., Furnas, G. W., Landauer, T. K., and Harshman, R. "Indexing by latent semantic analysis". Journal of the American Society for Information Science, 1990, 41:391--407.
[3]
Eriksson, G., Franzen, K., Olsson, F., Asker, L., and Liden, P. "Exploiting syntax when detecting protein names in text". In Proceedings of Workshop on Natural Language Processing in Biomedical Applications, 2002.
[4]
Fu, Y., Bauer, T., Mostafa, J., Palakal, M., & Mukhopadhyay, S. "Concept extraction and association from cancer literature". In Proceedings of the fourth international workshop on Web information and data management of ACM CIKM, 2002, 100--103.
[5]
Fukuda, K., Tsunoda, T., Tamura, A., and Takagi, T. "Toward information extraction: identifying protein names from biological papers". In Pac Symp Biocomput, 1998, 707--18.
[6]
Kazuhiro, S., and Mostafa, J. "An approach to protein name extraction using heuristics and a dictionary". Laboratory of Applied Information Research Tech Report 2003-2. Indiana University, Bloomington, IN, USA, 2003.
[7]
Rindflesch, T., Rajan, J., and Hunter, L. "Extracting molecular binding relationships from biomedical text". In Proceedings of the 6th Applied Natural Language Processing Conference, 2000, 188--195.
[8]
Salton, G. Introduction to modern information retrieval. McGraw-Hill, New York, 1983.
[9]
Thomas, J., Milward, D., Ouzounis, C., Pulman, S., and Carroll, M. "Automatic extraction of protein interactions from scientific abstracts". In Pac Symp Biocomput, 2000, 541--52.
[10]
Tou, J. T. and Gonzalez, R. C. Pattern Recognition Principles. Addision-Wcslcy, 1974.

Cited By

View all
  • (2005)Generating association graphs of non-cooccurring text objects using transitive methodsProceedings of the 2005 ACM symposium on Applied computing10.1145/1066677.1066713(141-145)Online publication date: 13-Mar-2005
  • (2003)A Probabilistic Model for Identifying Protein Names and their Name BoundariesProceedings of the IEEE Computer Society Conference on Bioinformatics10.5555/937976.938046Online publication date: 11-Aug-2003

Recommendations

Comments

Please enable JavaScript to view thecomments powered by Disqus.

Information & Contributors

Information

Published In

cover image ACM Conferences
JCDL '03: Proceedings of the 3rd ACM/IEEE-CS joint conference on Digital libraries
May 2003
393 pages
ISBN:0769519393

Sponsors

Publisher

IEEE Computer Society

United States

Publication History

Published: 27 May 2003

Check for updates

Qualifiers

  • Article

Conference

JCDL03
Sponsor:

Acceptance Rates

JCDL '03 Paper Acceptance Rate 54 of 216 submissions, 25%;
Overall Acceptance Rate 415 of 1,482 submissions, 28%

Contributors

Other Metrics

Bibliometrics & Citations

Bibliometrics

Article Metrics

  • Downloads (Last 12 months)0
  • Downloads (Last 6 weeks)0
Reflects downloads up to 23 Dec 2024

Other Metrics

Citations

Cited By

View all
  • (2005)Generating association graphs of non-cooccurring text objects using transitive methodsProceedings of the 2005 ACM symposium on Applied computing10.1145/1066677.1066713(141-145)Online publication date: 13-Mar-2005
  • (2003)A Probabilistic Model for Identifying Protein Names and their Name BoundariesProceedings of the IEEE Computer Society Conference on Bioinformatics10.5555/937976.938046Online publication date: 11-Aug-2003

View Options

Login options

View options

PDF

View or Download as a PDF file.

PDF

eReader

View online with eReader.

eReader

Media

Figures

Other

Tables

Share

Share

Share this Publication link

Share on social media